About: Clinical findings of patients with coronavirus disease 2019 in Jiangsu province, China: A retrospective, multi-center study

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About: Clinical findings of patients with coronavirus disease 2019 in Jiangsu province, China: A retrospective, multi-center study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical findings of patients with coronavirus disease 2019 in Jiangsu province, China: A retrospective, multi-center study
Creator	Wang, Jian Wei, Jie Zhao, Haiyan Zhao, Yun Zhu, Li Chen, Yuxin Huang, Rui Shan, Chun Xia, Juan Cao, Qi Xu, Tianmin Liu, Zou, Lei Chen, Xiaobing Cheng, Juan Guan, Xinying Hong, Shuqin Li, Chunyang Leyang, Xue Sang, Dawen Shao, Huaping Wang, Yinling Wuid, Chao Zhang, Biao Zhao, Xiang-An Zhu, Chuanwu Yan, Xiaomin
Source	Medline; PMC
abstract	Limited data are available for clinical characteristics of patients with coronavirus disease 2019 (COVID-19) outside Wuhan. This study aimed to describe the clinical characteristics of COVID-19 and identify the risk factors for severe illness of COVID-19 in Jiangsu province, China. Clinical data of hospitalized COVID-19 patients were retrospectively collected in 8 hospitals from 8 cities of Jiangsu province, China. Clinical findings of COVID-19 patients were described and risk factors for severe illness of COVID-19 were analyzed. By Feb 10, 2020, 202 hospitalized patients with COVID-19 were enrolled. The median age of patients was 44.0 years (interquartile range, 33.0–54.0). 55 (27.2%) patients had comorbidities. At the onset of illness, the common symptoms were fever (156 [77.2%]) and cough (120 [59.4%]). 66 (32.7%) patients had lymphopenia. 193 (95.5%) patients had abnormal radiological findings. 11 (5.4%) patients were admitted to the intensive care unit and none of the patients died. 23 (11.4%) patients had severe illness. Severe illness of COVID-19 was independently associated with body mass index (BMI) ≥ 28 kg/m(2) (odds ratio [OR], 9.219; 95% confidence interval [CI], 2.731 to 31.126; P<0.001) and a known history of type 2 diabetes (OR, 4.326; 95% CI, 1.059 to 17.668; P = 0.041). In this case series in Jiangsu Province, COVID-19 patients had less severe symptoms and had better outcomes than the initial COVID-19 patients in Wuhan. The BMI ≥ 28 kg/m(2) and a known history of type 2 diabetes were independent risk factors of severe illness in patients with COVID-19.
has issue date	2020-05-08(xsd:dateTime)
bibo:doi	10.1371/journal.pntd.0008280
bibo:pmid	32384078
has license	cc-by
sha1sum (hex)	b5524d4863eec7edc94c173b066d7efd9bef88ac
schema:url	https://doi.org/10.1371/journal.pntd.0008280
resource representing a document's title	Clinical findings of patients with coronavirus disease 2019 in Jiangsu province, China: A retrospective, multi-center study
has PubMed Central identifier	PMC7239492
has PubMed identifier	32384078
schema:publication	PLoS Negl Trop Dis
resource representing a document's body	covid:b5524d4863eec7edc94c173b066d7efd9bef88ac#body_text
is schema:about of	named entity 'ILLNESS' named entity 'NEGLECTED TROPICAL DISEASES' named entity '28120' named entity 'CLINICAL FINDINGS' named entity 'DESCRIBED' named entity 'IDENTIFY' named entity 'ENROLLED' named entity 'YEARS' named entity 'CONFIDENCE INTERVAL' named entity 'ABNORMAL' named entity '10%' named entity 'risk factors' named entity 'interquartile range' named entity 'risk factors' named entity 'Wuhan' named entity 'cough' named entity 'COVID-19' named entity 'Clinical data' named entity 'Jiangsu' named entity 'intensive care unit' named entity 'COVID' named entity 'China' named entity 'Clinical findings' named entity 'albumin' named entity 'Clinical findings' named entity 'Wuhan' named entity 'ground glass opacity' named entity 'Wuhan' named entity 'comorbidities' named entity 'antibiotic treatment' named entity 'COVID' named entity 'COVID' named entity 'obesity' named entity 'comorbidities' named entity 'CRP' named entity 'univariate analysis' named entity 'coronavirus infection' named entity 'Fisher exact test' named entity 'lymphocytes' named entity 'COVID' named entity 'corticosteroids' named entity 'mortality rate' named entity 'type 2 diabetes' named entity 'Jiangsu' named entity 'related conditions' named entity 'COVID-19' named entity 'Beijing' named entity 'cough' named entity 'etiologically' named entity 'COVID' named entity 'single center' named entity 'oseltamivir' named entity 'type 2 diabetes' named entity 'Wuhan' named entity 'statistically significant'

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