About: A critically ill patient after a colchicine overdose below the lethal dose: a case report

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A critically ill patient after a colchicine overdose below the lethal dose: a case report
Creator	Morimura, Naoto Doi, Kent Hirayama, Ichiro Hiruma, Takahiro Ueda, Yoshihiro
Source	PMC
abstract	BACKGROUND: Although 0.8 mg/kg is considered a lethal dose of colchicine, fatal cases of patients who followed a critical disease course after an intake below this lethal dose have been reported. CASE PRESENTATION: An 18-year-old Japanese woman who had taken an overdose of prescription colchicine (15 mg; 0.2 mg/kg) was brought to our emergency out-patient department. Although her colchicine intake was below 0.8 mg/kg (considered the lethal dose), she reached a critical state and underwent three phases characterizing colchicine poisoning (gastrointestinal symptoms, multiple organ failure, and recovery). Her condition was critical, with a Sequential Organ Failure Assessment score of a maximum of 14. CONCLUSIONS: Patients might reach a critical stage after colchicine ingestion at a non-lethal dose. Thus, it might be necessary to review which dose of colchicine should be considered lethal.
has issue date	2018-07-04(xsd:dateTime)
bibo:doi	10.1186/s13256-018-1737-5
bibo:pmid	29970148
has license	cc-by
sha1sum (hex)	b4f55f77b397a1ab75c6169ee5d4c85548d9340e
schema:url	https://doi.org/10.1186/s13256-018-1737-5
resource representing a document's title	A critically ill patient after a colchicine overdose below the lethal dose: a case report
has PubMed Central identifier	PMC6030797
has PubMed identifier	29970148
schema:publication	J Med Case Rep
resource representing a document's body	covid:b4f55f77b397a1ab75c6169ee5d4c85548d9340e#body_text
is schema:about of	named entity 'overdose' named entity 'RECOVERY' named entity 'DOSE' named entity 'YEAR' named entity 'OUT-PATIENT' named entity 'SYMPTOMS' named entity 'MIGHT BE' named entity 'COLCHICINE POISONING' named entity 'CASES' named entity 'disease' named entity 'Although' named entity 'Case' named entity 'overdose' named entity 'colchicine' named entity 'out-patient' named entity 'colchicine' named entity 'colchicine' named entity 'lethal dose' named entity 'blood tests' named entity 'noradrenaline' named entity 'vomiting' named entity 'critical stage' named entity 'colchicine' named entity 'inoculated' named entity 'therapeutic drug' named entity 'critical stage' named entity 'colchicine' named entity 'sodium' named entity 'LD50' named entity 'abdominal pain' named entity 'γ-GT' named entity 'vasopressin' named entity 'hepatic dysfunction' named entity 'Behçet's disease' named entity 'drug interaction' named entity 'bacteria' named entity 'vital signs' named entity 'colchicine' named entity 'vasopressor' named entity 'gastrointestinal symptoms' named entity 'multiple organ failure' named entity 'colchicine' named entity 'overdose' named entity 'medical history' named entity 'critical stage' named entity 'lactic acid bacteria' named entity 'Lactobacillus acidophilus' named entity 'upper abdominal' named entity 'organ' named entity 'Bifidobacterium longum' named entity 'tobacco' named entity 'hemodynamic' named entity 'steroids' named entity 'colchicine' named entity 'myelosuppression' named entity 'colchicine' named entity 'drank alcohol' named entity 'pregabalin' named entity 'colchicine' named entity 'schizophrenia' named entity '36 hours' named entity 'potassium' named entity 'critical stage' named entity 'beats per minute' named entity 'computed tomography' named entity 'multiple organ failure' named entity 'lactic acid' named entity 'anuria' named entity 'tablets' named entity 'D-dimer' named entity 'hepatic dysfunction' named entity 'neurological' named entity 'Colchicine' named entity 'hair loss' named entity 'infusion' named entity 'colchicine' named entity 'blood pressure'

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