About: Comparative proteome analysis of tracheal tissues in response to infectious bronchitis coronavirus, Newcastle disease virus, and avian influenza virus H9 subtype virus infection

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About: Comparative proteome analysis of tracheal tissues in response to infectious bronchitis coronavirus, Newcastle disease virus, and avian influenza virus H9 subtype virus infection Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Comparative proteome analysis of tracheal tissues in response to infectious bronchitis coronavirus, Newcastle disease virus, and avian influenza virus H9 subtype virus infection
Creator	Han, Zongxi Kong, Xiangang Liu, Shengwang Shao, Yuhao Sun, Junfeng Cao, Zhongzan
source	Medline; PMC
abstract	Infectious bronchitis coronavirus (IBV), Newcastle disease virus (NDV), and avian influenza virus (AIV) H9 subtype are major pathogens of chickens causing serious respiratory tract disease and heavy economic losses. To better understand the replication features of these viruses in their target organs and molecular pathogenesis of these different viruses, comparative proteomic analysis was performed to investigate the proteome changes of primary target organ during IBV, NDV, and AIV H9 infections, using 2D‐DIGE followed MALDI‐TOF/TOF‐MS. In total, 44, 39, 41, 48, and 38 proteins were identified in the tracheal tissues of the chickens inoculated with IBV (ck/CH/LDL/97I, H120), NDV (La Sota), and AIV H9, and between ck/CH/LDL/97I and H120, respectively. Bioinformatics analysis showed that IBV, NDV, and AIV H9 induced similar core host responses involved in biosynthetic, catabolic, metabolic, signal transduction, transport, cytoskeleton organization, macromolecular complex assembly, cell death, response to stress, and immune system process. Comparative analysis of host response induced by different viruses indicated differences in protein expression changes induced by IBV, NDV, and AIV H9 may be responsible for the specific pathogenesis of these different viruses. Our result reveals specific host response to IBV, NDV, and AIVH9 infections and provides insights into the distinct pathogenic mechanisms of these avian respiratory viruses.
has issue date	2014-04-17(xsd:dateTime)
bibo:doi	10.1002/pmic.201300404
bibo:pmid	24610701
has license	no-cc
sha1sum (hex)	b3370a85527782792c15d5992619f9f44a34b4ec
schema:url	https://doi.org/10.1002/pmic.201300404
resource representing a document's title	Comparative proteome analysis of tracheal tissues in response to infectious bronchitis coronavirus, Newcastle disease virus, and avian influenza virus H9 subtype virus infection
has PubMed Central identifier	PMC7167649
has PubMed identifier	24610701
schema:publication	Proteomics
resource representing a document's body	covid:b3370a85527782792c15d5992619f9f44a34b4ec#body_text
is schema:about of	named entity 'infectious bronchitis' named entity 'NDV' named entity 'biosafety levels' named entity 'pathogenic viruses' named entity 'RSV' named entity 'protein' named entity 'Viral load' named entity 'EIF5A2' named entity 'lung' named entity 'SDS-PAGE' named entity 'pathogenesis' named entity 'IBV' named entity 'virus' named entity 'pathogenesis' named entity 'epithelium' named entity 'SDS-PAGE' named entity 'primers' named entity 'PPIA' named entity 'LDL' named entity 'immune response' named entity 'Itk' named entity 'IBV' named entity 'protein' named entity 'LDL' named entity 'Japan' named entity 'Galectin-1' named entity 'Tracheal' named entity 'epithelium' named entity 'IBV' named entity 'Tris-HCl' named entity 'secretion' named entity 'LDL' named entity 'Cy3' named entity 'etiological' named entity 'infection' named entity 'protein expression' named entity 'AIV' named entity 'anti-inflammatory' named entity 'virulent' named entity 'frameshifting' named entity 'lower respiratory tract' named entity 'trachea' named entity 'GE Healthcare' named entity 'LGALS1' named entity 'cell lines' named entity 'primers' named entity 'NUMA' named entity 'LMNA' named entity 'immune cells' named entity 'aldo-keto reductase' named entity 'IBV' named entity 'NDV' named entity 'protein expression' named entity 'virus' named entity 'ANXA1' named entity 'hemoglobin' named entity 'nuclear lamina' named entity 'nucleocapsid protein' named entity 'receptor' named entity 'inflammatory responses' named entity 'ubiquitin-proteasome pathway' named entity 'viral adsorption' named entity 'NDV' named entity 'methionine' named entity 'DF-1' named entity 'PPIA' named entity 'tracheal' named entity 'AIV' named entity 'LDL' named entity 'ANXA1' named entity 'pH 3' named entity 'HCV' named entity 'cytoplasm' named entity 'EIF5A2' named entity 'upregulation' named entity 'antibody'

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