About: Unexpected BP Sensitivity to Angiotensin II in a Patient With Coronavirus Disease 2019, ARDS, and Septic Shock

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About: Unexpected BP Sensitivity to Angiotensin II in a Patient With Coronavirus Disease 2019, ARDS, and Septic Shock Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Unexpected BP Sensitivity to Angiotensin II in a Patient With Coronavirus Disease 2019, ARDS, and Septic Shock
Creator	Khan, Wieruszewski, Patrick Azad, Nabila Bartlett, Brian Chowdhury, Arnab Das, Subhraleena Jain, Nitesh Khan, Syed Kolar, Gururaj Subla, Mir Taji, Jamil Wang, Hanyin Syed, Anjum
Source	Elsevier; Medline; PMC
abstract	We report the case of an 88-year-old man with coronavirus disease 2019 (COVID-19) who presented with ARDS and septic shock. The patient had exquisite BP sensitivity to low-dose angiotensin II (Ang-2), allowing for rapid liberation from high-dose vasopressors. We hypothesize that sensitivity to Ang-2 might be related to biological effect of severe acute respiratory syndrome coronavirus 2 infection. The case is suggestive of a potential role for synthetic Ang-2 for patients with COVID-19 and septic shock. Further studies are needed to confirm our observed clinical efficacy.
has issue date	2020-04-23(xsd:dateTime)
bibo:doi	10.1016/j.chest.2020.04.015
bibo:pmid	32335068
has license	els-covid
sha1sum (hex)	b223b6c4be8a1740b0c9e80ab8b96e6c66b22690
schema:url	https://doi.org/10.1016/j.chest.2020.04.015
resource representing a document's title	Unexpected BP Sensitivity to Angiotensin II in a Patient With Coronavirus Disease 2019, ARDS, and Septic Shock
has PubMed Central identifier	PMC7194656
has PubMed identifier	32335068
schema:publication	Chest
resource representing a document's body	covid:b223b6c4be8a1740b0c9e80ab8b96e6c66b22690#body_text
is schema:about of	named entity 'coronavirus disease 2019' named entity 'COVID-19' named entity 'BIOLOGICAL EFFECT' covid:arg/b223b6c4be8a1740b0c9e80ab8b96e6c66b22690 named entity 'ARDS' named entity 'needed' named entity 'COVID' named entity 'COVID' named entity 'septic shock' named entity 'biological effect' named entity 'angiotensin II' named entity 'septic shock' named entity 'neuromuscular blocker' named entity 'oxygen saturation' named entity 'infectious diseases' named entity 'neuromuscular blocker' named entity 'critically ill' named entity 'hemodynamic' named entity 'ICU' named entity 'SARS-CoV-2' named entity 'ventilator' named entity 'ACE' named entity 'COVID-19' named entity 'mm Hg' named entity 'vasopressor' named entity 'COVID' named entity 'type 1' named entity 'ARDS' named entity 'ACE inhibitor' named entity 'azithromycin' named entity 'SARS-CoV-2' named entity 'COVID' named entity 'ACE' named entity 'coronavirus' named entity 'ACE inhibitor' named entity 'infection' named entity 'cough' named entity 'SARS-CoV-2' named entity 'SARS-CoV' named entity 'vasopressor' named entity 'SARS-CoV-2' named entity 'ACE2' named entity 'SARS-CoV-2' named entity 'septic shock' named entity 'angiotensin-converting enzyme' named entity 'septic shock' named entity 'C-reactive protein' named entity 'vasopressor' named entity 'ARDS' named entity 'dialysis' named entity 'vascular resistance' named entity 'angiotensin' named entity 'ICU' named entity 'ICU' named entity 'ARDS' named entity 'COVID' named entity 'tachycardic' named entity 'Rochester, MN' named entity 'lisinopril' named entity 'biological process' named entity 'hypotensive' named entity 'receptor' named entity 'norepinephrine' named entity 'refractory' named entity 'lung' named entity 'ACE' named entity 'ACE inhibitor' named entity 'case report' named entity 'hydroxychloroquine'

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