9 Subgroup analyses showed that , among the general population , application of ACEI / ARB 10 therapy was associated with reduced risks of all - cause death ( OR : 0 . 31 , 95 % CI : 0 . 13 - 0 . 75 ) , and 11 the risk of severe COVID - 19 ( OR : 0 . 79 , 95 % CI : 0 . 60 - 1