About: Diabetic patients with COVID-19 infection are at higher risk of ICU admission and poor short-term outcome

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Diabetic patients with COVID-19 infection are at higher risk of ICU admission and poor short-term outcome
Creator	Rigatelli, Gianluca Roncon, Loris Zuin, Marco Zuliani, Giovanni
Source	Elsevier; Medline; PMC
abstract	BACKGROUND: The prognostic significance of diabetes mellitus (DM) in patients with coronavirus 2019 disease (COVID-19) remains unknown. OBJECTIVES: To assess the risk of ICU admission and morality risk in diabetic COVID-19 patients. STUDY DESING: A database search was conducted to identify studies comparing diabetic COVID-19 patients hospitalized in intensive care unit (ICU) and those reporting the overall mortality of these patients published up to March 25, 2020 within MEDLINE, Scopus and Web of Science. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed in abstracting data and assessing validity. Quality assessment was performed using the Newcastle-Ottawa quality assessment scale. The main outcome was the risk of ICU admission in diabetic patients with COVID-19 infection while the second was the mortality risk in overall diabetic COVID-19 patients. Data were pooled using the Mantel-Haenszel random effects models with odds ratio (OR) as the effect measure with the related 95 % confidence interval (CI). Statistical heterogeneity between groups was measured using the Higgins I(2) statistic. RESULTS: Among 1382 patients (mean age 51.5 years, 798 males), DM resulted to be the second more frequent comorbidities. Diabetic patients resulted to have a significant increased risk of ICU admission (OR: 2.79, 95 % CI 1.85–4.22, p < 0.0001, I(2) = 46 %). In 471 patients (mean age 56.6 years, 294 males) analysed for the secondary outcome diabetic subjects resulted to be at higher mortality risk (OR 3.21, 95 % CI 1.82–5.64, p < 0.0001, I(2) = 16 %). CONCLUSIONS: Diabetic patients with COVID-19 patients are at higher risk of ICU admission and show an higher mortality risk.
has issue date	2020-04-09(xsd:dateTime)
bibo:doi	10.1016/j.jcv.2020.104354
bibo:pmid	32305882
has license	no-cc
sha1sum (hex)	af90a81d5a27b891abe79ba66eddfc4bc1bb14b6
schema:url	https://doi.org/10.1016/j.jcv.2020.104354
resource representing a document's title	Diabetic patients with COVID-19 infection are at higher risk of ICU admission and poor short-term outcome
has PubMed Central identifier	PMC7195018
has PubMed identifier	32305882
schema:publication	J Clin Virol
resource representing a document's body	covid:af90a81d5a27b891abe79ba66eddfc4bc1bb14b6#body_text
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