About: The Association of Newly Identified Respiratory Viruses with Lower Respiratory Tract Infections in Korean Children, 2000

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About: The Association of Newly Identified Respiratory Viruses with Lower Respiratory Tract Infections in Korean Children, 2000–2005 Goto Sponge NotDistinct Permalink

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Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The Association of Newly Identified Respiratory Viruses with Lower Respiratory Tract Infections in Korean Children, 2000–2005
Creator	Lee, Jin Lee, Jun Choi, Eun Kim, Nam Kim, So Kim, Sun Lee, Hoan Park, Ji Song, Eun Yeon, Ji Eun, Byung
Source	Medline; PMC
abstract	Background. This study was performed to evaluate the associations of newly recognized viruses, namely, human metapneumovirus (hMPV), human coronavirus (HCoV)–NL63, and human bocavirus (HBoV) with lower respiratory tract infections (LRTIs) in previously healthy children. Methods. To determine the prevalences of 11 viruses—respiratory syncytial virus (RSV), adenovirus, rhinovirus, parainfluenza viruses (PIVs) 1 and 3, influenza viruses A and B, hMPV, HCoV, HCoV-NL63, and HBoV—among infants or children with LRTIs, in association with their epidemiologic characteristics, we performed multiplex reverse-transcriptase polymerase chain reaction on nasopharyngeal aspirates obtained from 515 children 5 years old with LRTIs during the period 2000–2005. Results. Viruses were identified in 312 (60.6%) of the 515 patients. RSV was detected in 122 (23.7%), HBoV in 58 (11.3%), adenovirus in 35 (6.8%), PIV-3 in 32 (6.2%), rhinovirus in 30 (5.8%), hMPV in 24 (4.7%), influenza A in 24 (4.7%), PIV-1 in 9 (1.7%), influenza B in 9 (1.7%), and HCoV-NL63 in 8 (1.6%). Coinfections with 2 viruses were observed in 36 patients (11.5%). Twenty-two patients (37.9%) infected with HBoV had a coinfection. Bronchiolitis was frequently diagnosed in patients who tested positive for RSV, PIV-3, or rhinovirus, whereas influenza A, PIV-1, and HCoV-NL63 were commonly found in patients with croup. The age distributions of patients with viral infections differed; notably, RSV was responsible for 77% of LRTIs that occurred in infants 3 months old. The number of hMPV infections peaked between February and April, whereas the number of HCoV-NL63 infections peaked between April and May. Conclusions. This study describes the features of LRTIs associated with newly identified viruses in children, compared with those associated with known viruses. Additional investigations are required to define the role of HBoV in LRTI.
has issue date	2006-09-01(xsd:dateTime)
bibo:doi	10.1086/506350
bibo:pmid	16886150
has license	no-cc
sha1sum (hex)	af471147dddd7e5701bf4919ab4b7aef45a43d7b
schema:url	https://doi.org/10.1086/506350
resource representing a document's title	The Association of Newly Identified Respiratory Viruses with Lower Respiratory Tract Infections in Korean Children, 2000–2005
has PubMed Central identifier	PMC7107986
has PubMed identifier	16886150
schema:publication	Clin Infect Dis
resource representing a document's body	covid:af471147dddd7e5701bf4919ab4b7aef45a43d7b#body_text
is schema:about of	named entity 'RESPIRATORY VIRUSES' named entity 'ASSOCIATION' named entity 'IDENTIFIED' named entity 'KOREAN' named entity '2000' named entity 'CHILDREN' named entity 'LOWER RESPIRATORY TRACT INFECTIONS' named entity 'NEWLY' named entity 'Viruses' named entity 'auscultation' named entity 'immunofluorescent' named entity 'RSV' named entity 'viruses' named entity 'viruses' named entity 'MgCl' named entity 'LRTI' named entity 'rhinovirus' named entity 'coinfected' named entity 'primers' named entity 'viruses' named entity 'viral culture' named entity 'coronavirus' named entity 'croup' named entity 'causative agent' named entity 'selection bias' named entity 'rhinovirus' named entity 'RSV' named entity 'Seoul National University' named entity 'hMPV' named entity 'HCoV-NL63' named entity 'human metapneumovirus' named entity 'upper respiratory tract infections' named entity 'influenza' named entity 'stridor' named entity 'HCoV-NL63' named entity 'pathogen' named entity 'viruses' named entity 'pneumonia' named entity 'respiratory diseases' named entity 'Fever' named entity 'nasopharyngeal' named entity 'reverse transcriptase' named entity 'human bocavirus' named entity 'cough' named entity 'clinical features' named entity 'viral RNA' named entity 'bronchiolitis' named entity 'rhinovirus' named entity 'infection' named entity 'coinfected' named entity 'negative control' named entity 'croup' named entity 'RT-PCR' named entity 'DNA polymerase' named entity 'respiratory tracts' named entity 'coinfection' named entity 'Seoul National University Bundang Hospital' named entity 'HCoV-NL63' named entity 'early summer' named entity 'molecular methods' named entity 'viruses' named entity 'cell culture' named entity 'clinical characteristics' named entity 'symptoms and signs' named entity 'principal investigator' named entity 'rhinovirus' named entity 'asthma exacerbations' named entity 'OC43' named entity 'PCR' named entity 'HCoV-NL63' named entity 'Applied Biosystems'

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