About: Introduction of Asian canine parvovirus in Europe through dog importation

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Introduction of Asian canine parvovirus in Europe through dog importation
Creator	Decaro, \| Desario, \| Di Bella, \| Gucciardi, \| Guercio, \| Lorusso, \| Macaluso, \| Mira, F Purpari, \|
Source	Medline; PMC
abstract	Canine parvovirus (CPV) is an important infectious agent of domestic and wild carnivores, responsible for severe and often fatal haemorrhagic gastroenteritis and leukopenia. This paper reports the genomic characterization of a CPV strain collected from a dog recently imported to Italy from Thailand. The virus was detected in all tissue samples collected. The whole genome encompassing the two open reading frames encoding for non‐structural (NS1/NS2) and structural (VP1/VP2) proteins was amplified and sequenced. On the basis of genetic analysis of the VP2 gene, the isolate was characterized as CPV‐2c, but it presented genetic signatures typical of Asian strains. Sequence analysis revealed the presence of amino acid changes never observed in European CPV‐2c strains (NS1: Ile60Val, Tyr544Phe, Glu545Val, Leu630Pro; VP2: Ala5Gly, Phe267Tyr, Tyr324Ile, Gln370Arg). By phylogenetic analysis of full‐length VP2 gene, the analysed strain clustered together with Asian viruses. Therefore, a possible introduction of the virus from Asia through the imported dog was suggested, thus confirming the important role of movement of dogs in the global spread of viruses. In addition, full‐length genome analysis could help better trace the spread of canine viruses through different continents.
has issue date	2017-11-13(xsd:dateTime)
bibo:doi	10.1111/tbed.12747
bibo:pmid	29134762
has license	no-cc
sha1sum (hex)	aeebd51b3ae190ee2da47fd92dad70810398ca9e
schema:url	https://doi.org/10.1111/tbed.12747
resource representing a document's title	Introduction of Asian canine parvovirus in Europe through dog importation
has PubMed Central identifier	PMC7169687
has PubMed identifier	29134762
schema:publication	Transbound Emerg Dis
resource representing a document's body	covid:aeebd51b3ae190ee2da47fd92dad70810398ca9e#body_text
is schema:about of	named entity 'dog' named entity 'importation' named entity 'canine parvovirus' named entity 'Laos' named entity 'Thailand' named entity 'Italy' named entity 'DNA Polymerase' named entity 'canine herpesvirus' named entity 'RFLP' named entity 'genome' named entity 'Bangkok' named entity 'type 1' named entity 'Thailand' named entity 'clade' named entity 'virological' named entity 'electrophoresis' named entity 'Asian' named entity 'MgCl' named entity 'clinical signs' named entity 'canine distemper virus' named entity 'Thailand' named entity 'genome sequences' named entity 'epidemiological' named entity 'liver' named entity 'clade' named entity 'beta barrel' named entity 'clades' named entity 'restriction endonuclease' named entity 'epidemiology' named entity 'primers' named entity 'Asian' named entity 'Italy' named entity 'primer' named entity 'China' named entity 'PCR' named entity 'Vientiane' named entity 'spleen' named entity 'Phylogenetic analysis' named entity 'Promega' named entity 'NS2' named entity 'Thailand' named entity 'Brazil' named entity 'ethidium bromide' named entity 'PCR' named entity 'viral capsid' named entity 'amplicons' named entity 'Europe' named entity 'lungs' named entity 'capsid' named entity 'PCR' named entity 'intestine' named entity 'dog' named entity 'Asia' named entity 'nucleotide sequences' named entity 'India' named entity 'necropsy' named entity 'giant panda' named entity 'canine coronavirus' named entity 'Asian' named entity 'synonymous substitutions' named entity 'capsid' named entity 'genomes' named entity 'RNA' named entity 'Asia' named entity 'dNTP' named entity 'CDV' named entity 'fever' named entity 'main sequence' named entity 'type 2' named entity 'clade' named entity 'Italy' named entity 'dog' named entity 'dog'

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