About: Improvement in the survival rates of extracorporeal membrane oxygenation-supported respiratory failure patients: a multicenter retrospective study in Korean patients

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About: Improvement in the survival rates of extracorporeal membrane oxygenation-supported respiratory failure patients: a multicenter retrospective study in Korean patients Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Improvement in the survival rates of extracorporeal membrane oxygenation-supported respiratory failure patients: a multicenter retrospective study in Korean patients
Creator	Kim, Jung-Hyun Hong, Sang-Bum Park, Sunghoon Lee, Sang-Min Cho, Young-Jae Yoo, Jung-Wan Chang, Youjin Cho, Kang, Byung Oh, Jin Park, Seung Park, So Sim, Yun Woo, Hyun Chung, Chi Jung, Jae-Seung Koo, So-My Seong Baek, Moon
Source	PMC
abstract	BACKGROUND: Although the utilization of extracorporeal membrane oxygenation (ECMO) is increasing and its technology is evolving, only a few epidemiologic reports have described the uses and outcomes of ECMO. The aim of this study was to investigate the changes in utilization and survival rate in patients supported with ECMO for severe respiratory failure in Korea. METHODS: This was a multicenter study on consecutive patients who underwent ECMO across 16 hospitals in Korea. The records of all patients who required ECMO for acute respiratory failure between 2012 and 2015 were retrospectively reviewed, and the utilization of ECMO was analyzed over time. RESULTS: During the study period, 5552 patients received ECMO in Korea as a whole, and a total of 2472 patients received ECMO at the participating 16 hospitals. We analyzed 487 (19.7%) patients who received ECMO for respiratory failure. The number of ECMO procedures provided for respiratory failure increased from 104 to 153 during the study period. The in-hospital survival rate increased from 30.8% to 35.9%. The use of prone positioning increased from 6.8% to 49.0% (p < 0.001), and the use of neuromuscular blockers also increased from 28.2% to 58.2% (p < 0.001). Multiple regression analysis showed that old age (OR 1.038 (95% CI 1.022, 1.054)), use of corticosteroid (OR 2.251 (95% CI 1.153, 4.397)), continuous renal replacement therapy (OR 2.196 (95% CI 1.135, 4.247)), driving pressure (OR 1.072 (95% CI 1.031, 1.114)), and prolonged ECMO duration (OR 1.020 (95% CI 1.003, 1.038)) were associated with increased odds of mortality. CONCLUSIONS: Utilization of ECMO and survival rates of patients who received ECMO for respiratory failure increased over time in Korea. The use of pre-ECMO prone positioning and neuromuscular blockers also increased during the same period.
has issue date	2019-01-03(xsd:dateTime)
bibo:doi	10.1186/s13054-018-2293-5
bibo:pmid	30606235
has license	cc-by
sha1sum (hex)	ae56d60debc175395e6269fc5bf9184291e71a56
schema:url	https://doi.org/10.1186/s13054-018-2293-5
resource representing a document's title	Improvement in the survival rates of extracorporeal membrane oxygenation-supported respiratory failure patients: a multicenter retrospective study in Korean patients
has PubMed Central identifier	PMC6318967
has PubMed identifier	30606235
schema:publication	Crit Care
resource representing a document's body	covid:ae56d60debc175395e6269fc5bf9184291e71a56#body_text
is schema:about of	named entity 'Methods' named entity 'membrane oxygenation' named entity 'The records' named entity 'utilization' named entity 'REQUIRED' named entity 'USES' named entity 'evolving' named entity 'ECMO' named entity 'Korea' named entity 'patients' named entity 'Korean' named entity 'retrospective study' named entity 'survival rate' named entity 'ECMO' named entity 'ECMO' named entity 'survival rates' named entity 'retrospective study' named entity 'retrospectively' named entity 'ECMO' named entity 'APACHE II' named entity 'selection bias' named entity 'ECMO' named entity 'ECMO' named entity 'continuous renal replacement therapy' named entity 'survival rate' named entity 'weaning' named entity 'survival rates' named entity 'acute respiratory failure' named entity 'mechanical ventilation' named entity 'stroke' named entity 'ECMO' named entity 'central nervous' named entity 'solid tumors' named entity 'nitric oxide' named entity 'peak inspiratory pressure' named entity 'epileptic syndrome' named entity 'Fisher's exact test' named entity 'respiratory failure' named entity 'respiratory failure' named entity 'stroke' named entity 'United States' named entity 'ECMO' named entity 'study protocol' named entity 'CNS' named entity 'Kruskal-Wallis test' named entity 'cardiac arrest' named entity 'severe respiratory failure' named entity 'central nervous' named entity 'COPD' named entity 'interquartile range' named entity 'SOFA score' named entity 'survival rate' named entity 'ARDS' named entity 'interquartile range' named entity 'ECMO' named entity 'ELSO' named entity 'ECMO' named entity 'Extracorporeal Life Support Organization' named entity 'respiratory failure' named entity 'body mass index' named entity 'ECMO' named entity 'design of the study' named entity 'Germany' named entity 'ECMO'

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