About: The cirrhosis care Alberta (CCAB) protocol: implementing an evidence-based best practice order set for the management of liver cirrhosis - a hybrid type I effectiveness-implementation trial

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About: The cirrhosis care Alberta (CCAB) protocol: implementing an evidence-based best practice order set for the management of liver cirrhosis - a hybrid type I effectiveness-implementation trial Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The cirrhosis care Alberta (CCAB) protocol: implementing an evidence-based best practice order set for the management of liver cirrhosis - a hybrid type I effectiveness-implementation trial
Creator	Sia, Winnie Abdellatif, Dalia Abraldes, Juan Amaize Eboreime, Ejemai Bakshi, Neeja Campbell-Scherer, Denise Carbonneau, Michelle Congly, Stephen Faris, Peter Gramlich, Leah Green, Lee Hyde, Ashley Marr, Kaleb Ryan, David Sadler, Matthew Schaefer, Jeffrey Selvarajah, Vijeyakumar Shaheen, Abdel Spiers, Jude Sugars, Benjamin Tandon, Puneeta Tsuyuki, Ross Varghese, Jayant Westra, Yolande Zeman, Marilyn
Source	Medline; PMC
abstract	BACKGROUND: Liver cirrhosis is a leading cause of morbidity, premature mortality and acute care utilization in patients with digestive disease. In the province of Alberta, hospital readmission rates for patients with cirrhosis are estimated at 44% at 90 days. For hospitalized patients, multiple care gaps exist, the most notable stemming from i) the lack of a structured approach to best practice care for cirrhosis complications, ii) the lack of a structured approach to broader health needs and iii) suboptimal preparation for transition of care into the community. Cirrhosis Care Alberta (CCAB) is a 4-year multi-component pragmatic trial which aims to address these gaps. The proposed intervention is initiated at the time of hospitalization through implementation of a clinical information system embedded electronic order set for delivering evidence-based best practices under real-world conditions. The overarching objective of the CCAB trial is to demonstrate effectiveness and implementation feasibility for use of the order set in routine patient care within eight hospital sites in Alberta. METHODS: A mixed methods hybrid type I effectiveness-implementation design will be used to evaluate the effectiveness of the order set intervention. The primary outcome is a reduction in 90-day cumulative length of stay. Implementation outcomes such as reach, adoption, fidelity and maintenance will also be evaluated alongside other patient and service outcomes such as readmission rates, quality of care and cost-effectiveness. This theory-based trial will be guided by Normalization Process Theory, Consolidated Framework on Implementation Research (CFIR) and the Reach-Effectiveness-Adoption-Implementation-Maintenance (RE-AIM) Framework. DISCUSSION: The CCAB project is unique in its breadth, both in the comprehensiveness of the multi-component order set and also for the breadth of its roll-out. Lessons learned will ultimately inform the feasibility and effectiveness of this approach in “real-world” conditions as well as adoption and adaptation of these best practices within the rest of Alberta, other provinces in Canada, and beyond. TRIAL REGISTRATION: ClinicalTrials.gov: NCT04149223, November 4, 2019.
has issue date	2020-06-18(xsd:dateTime)
bibo:doi	10.1186/s12913-020-05427-8
bibo:pmid	32552833
has license	cc-by
sha1sum (hex)	ae0cd4ca843226182c9e77eedc1122725560aa01
schema:url	https://doi.org/10.1186/s12913-020-05427-8
resource representing a document's title	The cirrhosis care Alberta (CCAB) protocol: implementing an evidence-based best practice order set for the management of liver cirrhosis - a hybrid type I effectiveness-implementation trial
has PubMed Central identifier	PMC7301349
has PubMed identifier	32552833
schema:publication	BMC Health Serv Res
resource representing a document's body	covid:ae0cd4ca843226182c9e77eedc1122725560aa01#body_text
is schema:about of	named entity 'address' named entity '90 days' named entity 'conditions' named entity 'digestive disease' named entity 'Alberta' named entity 'IS A' named entity 'RATES' named entity 'LEADING' named entity 'YEAR' named entity 'AIMS' named entity 'cirrhosis' named entity 'care' named entity 'objective' named entity 'care' named entity 'hospitalized' named entity 'hospital readmission' named entity 'Alberta' named entity 'Cirrhosis' named entity 'cirrhosis' named entity 'acute care' named entity 'Liver cirrhosis' named entity 'world conditions' named entity 'embedded' named entity 'Phase 1' named entity 'ERIC' named entity 'AUD' named entity 'mixed effects models' named entity 'advance care planning' named entity 'AUD' named entity 'Cirrhosis' named entity 'AHS' named entity 'clinical setting' named entity 'medical errors' named entity 'Edmonton' named entity 'multimethods' named entity 'pharmacologic' named entity 'nursing staff' named entity 'AHS' named entity 'AUD' named entity 'cirrhosis' named entity 'hepatic encephalopathy' named entity 'prophylaxis' named entity 'EQ-5D' named entity 'over-dispersed' named entity 'health-related quality of life' named entity 'cirrhosis' named entity 'AHS' named entity 'access to healthcare' named entity 'KPIs' named entity 'Cirrhosis' named entity 'hepatic insufficiency' named entity 'health professionals' named entity 'cirrhosis' named entity 'caregiver' named entity 'CIS' named entity 'quality of life' named entity 'ICD-10'

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