About: Acute kidney injury in critically ill patients with 2009 influenza A (H1N1) viral pneumonia: an observational study

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About: Acute kidney injury in critically ill patients with 2009 influenza A (H1N1) viral pneumonia: an observational study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Acute kidney injury in critically ill patients with 2009 influenza A (H1N1) viral pneumonia: an observational study
Creator	Cardinal, P Ortega, C Arancibia, F Arancibia, Á Bagnulo, H Bagnulo, Á Bujedo, G Cardinal, Uruguay Cortés, I Cortés, Á Crottogini, Juan Donación, Hospital Echevarría, E Español, Hospital Esteban, A Esteban, Á Frutos, F Frutos, Á Hurtado, Argentina Hurtado, J Lorente, J Maciel, Hospital Nacional, Hospital Nin, N Palomar, El Posadas, Profesor Ríos, F Saldarini, F Santojanni, Francisco Soto, L Ugarte, S
Source	PMC
abstract	OBJECTIVE: To describe the incidence, risk factors, and impact on mortality of acute kidney injury (AKI) in patients with 2009 influenza A (H1N1) viral pneumonia requiring mechanical ventilation. DESIGN: Observational cohort study. PATIENTS AND METHODS: AKI was defined as risk, injury or failure, according to the RIFLE classification. Early and late AKI were defined as AKI occurring on intensive care unit (ICU) day 2 or before, or after ICU day 2, respectively. Demographic data and information on organ dysfunction were collected daily. RESULTS: Of 84 patients, AKI developed in 43 patients (51%). Twenty (24%) needed renal replacement therapy. Early and late AKI were found in 28 (33%) and 15 (18%) patients, respectively. Patients with AKI, as compared with patients without AKI, had higher Acute Physiology and Chronic Health Evaluation (APACHE) II score and ICU mortality (72% versus 39%, p < 0.01) and presented on admission more marked cardiovascular, respiratory, and hematological dysfunction. Patients with early but not late AKI presented on admission higher APACHE II score and more marked organ dysfunction, as compared with patients without AKI. ICU mortality was higher in late versus early AKI (93% versus 61%, p < 0.001). On multivariate analysis, only APACHE II score and late but not early AKI [odds ratio (OR) 1.1 (95% confidence interval 1.0–1.1) and 15.1 (1.8–130.7), respectively] were associated with mortality. CONCLUSIONS: AKI is a frequent complication of 2009 influenza A (H1N1) viral pneumonia. AKI developing after 2 days in ICU appears to be associated with different risk factors than early AKI, and is related to a higher mortality rate.
has issue date	2011-03-11(xsd:dateTime)
bibo:doi	10.1007/s00134-011-2167-7
bibo:pmid	21394630
has license	no-cc
sha1sum (hex)	adf409baff832a0289ebf52bc9e6c2148062152a
schema:url	https://doi.org/10.1007/s00134-011-2167-7
resource representing a document's title	Acute kidney injury in critically ill patients with 2009 influenza A (H1N1) viral pneumonia: an observational study
has PubMed Central identifier	PMC7095219
has PubMed identifier	21394630
schema:publication	Intensive Care Med
resource representing a document's body	covid:adf409baff832a0289ebf52bc9e6c2148062152a#body_text
is schema:about of	named entity 'PATIENTS' named entity 'cardiovascular' named entity 'AKI' named entity 'early' named entity 'late' named entity 'higher' named entity 'Results' named entity 'higher' named entity 'renal replacement therapy' named entity 'Demographic' named entity 'AKI' named entity 'patients' named entity 'collected' named entity 'score' named entity 'critically ill' named entity 'EARLY' named entity 'ACCORDING' named entity 'COHORT STUDY' named entity 'MORTALITY' named entity 'APA' named entity '2818' named entity 'COLLECTED' named entity 'PRESENTED' named entity 'ACUTE KIDNEY INJURY' named entity 'MULTIVARIATE ANALYSIS' named entity 'RISK' named entity 'INTENSIVE CARE UNIT' named entity 'VIRAL PNEUMONIA' named entity 'ORGAN' named entity 'DESIGN' named entity 'DEMOGRAPHIC DATA' named entity 'OBSERVATIONAL' named entity 'RESPIRATORY' named entity '2851' named entity 'FAILURE' named entity 'HIGHER' named entity 'RESULTS' named entity '0.001' named entity 'ACUTE PHYSIOLOGY AND CHRONIC HEALTH EVALUATION' named entity 'DAILY' named entity 'AND LATE' named entity '1.1' named entity 'CARDIOVASCULAR' named entity 'CHE' named entity 'RENAL REPLACEMENT THERAPY' named entity 'LATE' named entity 'INCIDENCE' named entity 'BUT' named entity 'OBJECTIVE' named entity 'INFLUENZA A' named entity 'RISK FACTORS'

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