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About:
Molecular epidemiology of chicken anaemia virus in sick chickens in China from 2014 to 2015
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An Entity of Type :
schema:ScholarlyArticle
, within Data Space :
covidontheweb.inria.fr
associated with source
document(s)
Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
title
Molecular epidemiology of chicken anaemia virus in sick chickens in China from 2014 to 2015
Creator
Zhang, Yanping
Cui, Hongyu
Gao, Xiang
Wang, Xiaomei
Wang, Yongqiang
Gao, Honglei
Gao, Yulong
Liu, Changjun
Qi, Xiaole
Liu, Aijing
Han, Chunyan
Tuo, Tianbei
Yan, Nana
Yao, Shuai
Hussainid, Altaf
topic
covid:ad9cec450f3304e01cb4b517de934ba18094ce43#this
source
Medline; PMC
abstract
Chicken anaemia virus (CAV), a member of the genus Gyrovirus, is the etiological agent of chicken infectious anaemia. CAV infects bone marrow-derived cells, resulting in severe anaemia and immunosuppression in young chickens and a compromised immune response in older birds. We investigated the molecular epidemiology of CAV in sick chickens in China from 2014 to 2015 and showed that the CAV-positive rate was 13.30%, in which mixed infection (55.56%) was the main type of infection. We isolated and identified 15 new CAV strains using different methods including indirect immunofluorescence assay and Western Blotting. We used overlapping polymerase chain reaction to map the whole genome of the strains. Phylogenetic analyses of the obtained sequences and related sequences available in GenBank generated four distinct groups (A–D). We built phylogenetic trees using predicted viral protein (VP) sequences. Unlike CAV VP2s and VP3s that were well conserved, the diversity of VP1s indicated that the new strains were virulent. Our epidemiological study provided new insights into the prevalence of CAV in clinical settings in recent years in China.
has issue date
2019-01-18
(
xsd:dateTime
)
bibo:doi
10.1371/journal.pone.0210696
bibo:pmid
30657774
has license
cc-by
sha1sum (hex)
ad9cec450f3304e01cb4b517de934ba18094ce43
schema:url
https://doi.org/10.1371/journal.pone.0210696
resource representing a document's title
Molecular epidemiology of chicken anaemia virus in sick chickens in China from 2014 to 2015
has PubMed Central identifier
PMC6338413
has PubMed identifier
30657774
schema:publication
PLoS One
resource representing a document's body
covid:ad9cec450f3304e01cb4b517de934ba18094ce43#body_text
is
http://vocab.deri.ie/void#inDataset
of
https://covidontheweb.inria.fr:4443/about/id/http/ns.inria.fr/covid19/ad9cec450f3304e01cb4b517de934ba18094ce43
is
schema:about
of
named entity 'SICK'
named entity 'INFECTION'
named entity 'STRAINS'
named entity 'MIXED INFECTION'
named entity 'USING'
named entity 'GENBANK'
named entity 'INVESTIGATED'
named entity 'GENUS GYROVIRUS'
named entity 'MOLECULAR EPIDEMIOLOGY'
named entity 'POLYMERASE CHAIN REACTION'
named entity 'MAIN'
named entity 'IMMUNOSUPPRESSION'
named entity 'CELLS'
named entity 'RELATED'
named entity '28A'
named entity 'IMMUNOFLUORESCENCE ASSAY'
named entity 'PROTEIN '
named entity 'ISOLATED'
named entity 'DIFFERENT'
named entity 'INDIRECT IMMUNOFLUORESCENCE'
named entity 'DIVERSITY'
named entity 'RESULTING IN'
named entity 'strains'
named entity 'prevalence'
named entity 'chickens'
named entity 'viral protein'
named entity 'groups'
named entity 'China'
named entity 'Our'
named entity 'Phylogenetic analyses'
named entity 'Molecular epidemiology'
named entity '2015'
named entity 'MOLECULAR EPIDEMIOLOGY'
named entity 'OBTAINED'
named entity 'TREES'
named entity 'WHOLE GENOME'
named entity 'INCLUDING'
named entity 'CHICKEN ANAEMIA VIRUS'
named entity 'MAP'
named entity 'GENERATED'
named entity 'PREVALENCE'
named entity 'OVERLAPPING'
named entity 'BONE MARROW'
named entity '2015'
named entity 'DERIVED'
named entity 'AGENT'
named entity 'CHICKEN'
named entity 'CAV'
named entity 'INFECTIOUS'
named entity 'SEQUENCES'
named entity 'IDENTIFIED'
named entity '30%'
named entity 'CHICKENS'
named entity 'CHICKEN ANAEMIA VIRUS'
named entity 'CHINA'
named entity 'YOUNG'
named entity 'CHICKENS'
named entity 'BIRDS'
named entity 'METHODS'
named entity 'USED'
named entity 'VIRULENT'
named entity 'SEVERE'
named entity 'ANAEMIA'
named entity 'IMMUNE RESPONSE'
named entity 'INDICATED'
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