About: COVID-19 Positive in Nasopharyngeal Swab but Negative in Peritoneal Fluid: Case Report of Perforated Appendicitis

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About: COVID-19 Positive in Nasopharyngeal Swab but Negative in Peritoneal Fluid: Case Report of Perforated Appendicitis Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	COVID-19 Positive in Nasopharyngeal Swab but Negative in Peritoneal Fluid: Case Report of Perforated Appendicitis
Creator	Gusz, John Vudayagiri, Lahari
source	PMC
abstract	COVID-19 has drastically changed hospital systems from a microcosmic to macrocosmic level, specifically for surgical practices worldwide. COVID-19 surgical guidelines are continuing to evolve as we deepen our understanding of the virus. A particular point of interest is the possibility of aerosolization of COVID-19 during laparoscopic procedures. There is much uncertainty of the pathogenicity of COVID-19 and insufficient data on the presence and extent of viral load in different body fluids, specifically in peritoneal fluid. We present a case of a 27-year-old male who was diagnosed with acute appendicitis and found to be COVID-19 positive postoperatively. Intraoperative peritoneal fluid sampling was obtained and tested for COVID-19 through real-time reverse transcription polymerase chain reaction (RT-PCR) targeting N1 and N2 proteins. COVID-19 was not detected in RT-PCR test in the peritoneal fluid collected; however, it was detected in the nasopharyngeal RT-PCR. The patient had prolonged stay in the hospital secondary to COVID-19 symptoms. Currently, there is very limited and inconclusive evidence on the presence of COVID-19 in peritoneal fluid. We present the first paper discussing perforated bowel, in which COVID-19 is not detected in peritoneal fluid. This case report provides more insight regarding shaping guidelines for surgeries in patients with COVID-19.
has issue date	2020-07-27(xsd:dateTime)
bibo:doi	10.7759/cureus.9412
has license	cc-by
sha1sum (hex)	ad2de2d051b3b5e006d4d472a94b69a2af36cf81
schema:url	https://doi.org/10.7759/cureus.9412
resource representing a document's title	COVID-19 Positive in Nasopharyngeal Swab but Negative in Peritoneal Fluid: Case Report of Perforated Appendicitis
has PubMed Central identifier	PMC7449633
resource representing a document's body	covid:ad2de2d051b3b5e006d4d472a94b69a2af36cf81#body_text
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