About: Detection of Host Response to Viral Respiratory Infection by Measurement of Messenger RNA for MxA, TRIM21, and Viperin in Nasal Swabs

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About: Detection of Host Response to Viral Respiratory Infection by Measurement of Messenger RNA for MxA, TRIM21, and Viperin in Nasal Swabs Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Detection of Host Response to Viral Respiratory Infection by Measurement of Messenger RNA for MxA, TRIM21, and Viperin in Nasal Swabs
Creator	Waris, Matti Peltola, Ville Rulli, Maris Toivonen, Laura Yahya, Mohamed
source	Medline; PMC
abstract	Respiratory viruses frequently cause symptomatic infections in children but are often detected also in healthy children. We investigated myxovirus resistance protein A (MxA), viperin, and tripartite-motif 21 (TRIM21) messenger RNA indexes in nasal swabs as potential biomarkers of viral respiratory infection in children. Respiratory viruses were detected by polymerase chain reaction in the same swabs. Nasal MxA and viperin indexes were increased in symptomatic virus-positive children. Nasal viperin index was found to be a robust marker of viral respiratory tract infection with a sensitivity of 80% and specificity of 94% in distinguishing children with symptomatic virus infections from asymptomatic virus-negative children.
has issue date	2017-11-01(xsd:dateTime)
bibo:doi	10.1093/infdis/jix458
bibo:pmid	28968760
has license	no-cc
sha1sum (hex)	ad28497455f362e948f80668074df8fe2af28c50
schema:url	https://doi.org/10.1093/infdis/jix458
resource representing a document's title	Detection of Host Response to Viral Respiratory Infection by Measurement of Messenger RNA for MxA, TRIM21, and Viperin in Nasal Swabs
has PubMed Central identifier	PMC7107421
has PubMed identifier	28968760
schema:publication	J Infect Dis
resource representing a document's body	covid:ad28497455f362e948f80668074df8fe2af28c50#body_text
is schema:about of	named entity 'MESSENGER RNA' named entity 'BUT' named entity 'INDEX' named entity 'VIRUS' named entity 'PROTEIN A' named entity 'VIRAL RESPIRATORY INFECTION' named entity 'SENSITIVITY' named entity 'MARKER' named entity 'viruses' named entity 'viral' covid:arg/ad28497455f362e948f80668074df8fe2af28c50 named entity 'HOST RESPONSE' named entity 'ROBUST' named entity 'RESPIRATORY VIRUSES' named entity 'DETECTED' named entity 'HEALTHY' named entity 'INDEXES' named entity 'MYXOVIRUS' named entity 'VIPERIN' named entity 'FOUND' named entity 'POTENTIAL' named entity 'SYMPTOMATIC' named entity 'CAUSE' named entity 'INVESTIGATED' named entity 'VIPERIN' named entity 'VIRAL RESPIRATORY INFECTION' named entity 'MEASUREMENT' named entity 'DETECTION OF HOST' named entity 'TRIM21' named entity 'MOTIF' named entity 'BIOMARKERS' named entity 'FREQUENTLY' named entity 'INCREASED' named entity 'MESSENGER RNA' named entity 'NEGATIVE' named entity 'INFECTIONS' named entity 'NASAL' named entity 'TRIPARTITE' named entity 'SPECIFICITY' named entity 'POLYMERASE CHAIN REACTION' named entity 'NASAL SWABS' named entity 'MXA' named entity 'RESPONSE TO' named entity 'DISTINGUISHING' named entity 'MXA' named entity 'RESISTANCE' named entity 'NASAL SWABS' named entity 'POSITIVE' named entity 'SWABS' named entity 'ASYMPTOMATIC' named entity 'CHILDREN' named entity '80%' named entity 'VIRAL RESPIRATORY TRACT INFECTION' named entity 'Respiratory' named entity 'protein' named entity 'viral' named entity 'MxA' named entity 'sensitivity' named entity 'MxA' named entity 'virus' named entity 'polymerase chain reaction' named entity 'viperin' named entity 'Viperin' named entity 'viruses' named entity 'TRIM21' named entity 'RTI' named entity 'bacterial lipopolysaccharide' named entity 'virus infections' named entity 'virus' named entity 'mRNA expression' named entity 'viperin' named entity 'MMR' named entity 'mRNA' named entity 'TRIM21' named entity 'virus' named entity '1.02' named entity 'bacterial infections'

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