About: Clinical characteristics of 34 COVID-19 patients admitted to intensive care unit in Hangzhou, China

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About: Clinical characteristics of 34 COVID-19 patients admitted to intensive care unit in Hangzhou, China Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical characteristics of 34 COVID-19 patients admitted to intensive care unit in Hangzhou, China
Creator	Pan, Jian Zheng, Yi Cai, Hong-Liu Fang, Qiang Xu, Mi Fang, Xue-Ling Sun, Li-Jun Zhang, Yun-Tao
Source	Medline; PMC
abstract	OBJECTIVE: This study summarizes and compares clinical and laboratory characteristics of 34 patients admitted to the intensive care unit (ICU) for complications from coronavirus disease 2019 (COVID-19) at the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China from Jan. 22 to Mar. 5, 2020. METHODS: A total of 34 patients were divided into two groups, including those who required noninvasive ventilation (NIV) and invasive mechanical ventilation (IMV) with additional extracorporeal membrane oxygenation (ECMO) in 11 patients. Clinical features of COVID-19 patients were described and the parameters of clinical characteristics between the two groups were compared. RESULTS: The rates of the acute cardiac and kidney complications were higher in IMV cases than those in NIV cases. Most patients had lymphocytopenia on admission, with lymphocyte levels dropping progressively on the following days, and the more severe lymphopenia developed in the IMV group. In both groups, T lymphocyte counts were below typical lower limit norms compared to B lymphocytes. On admission, both groups had higher than expected amounts of plasma interleukin-6 (IL-6), which over time declined more in NIV patients. The prothrombin time was increased and the levels of platelet, hemoglobin, blood urea nitrogen (BUN), D-dimer, lactate dehydrogenase (LDH), and IL-6 were higher in IMV cases compared with NIV cases during hospitalization CONCLUSIONS: Data showed that the rates of complications, dynamics of lymphocytopenia, and changes in levels of platelet, hemoglobin, BUN, D-dimer, LDH and IL-6, and prothrombin time in these ICU patients were significantly different between IMV and NIV cases.
has issue date	2020-05-20(xsd:dateTime)
bibo:doi	10.1631/jzus.b2000174
bibo:pmid	32425003
has license	no-cc
sha1sum (hex)	ac33ab37d9107586f52d849b1970ca84aed93e0d
schema:url	https://doi.org/10.1631/jzus.b2000174
resource representing a document's title	Clinical characteristics of 34 COVID-19 patients admitted to intensive care unit in Hangzhou, China
has PubMed Central identifier	PMC7238397
has PubMed identifier	32425003
schema:publication	J Zhejiang Univ Sci B
resource representing a document's body	covid:ac33ab37d9107586f52d849b1970ca84aed93e0d#body_text
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