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About:
Extracorporeal membrane oxygenation as a bridge to lung transplantation: analysis of Korean organ transplantation registry (KOTRY) data
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covidontheweb.inria.fr
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Academic Article
research paper
schema:ScholarlyArticle
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Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Extracorporeal membrane oxygenation as a bridge to lung transplantation: analysis of Korean organ transplantation registry (KOTRY) data
Creator
Lee, Jin
Choi, Sun
Jeon, Kyeongman
Ko, Ryoung-Eun
Jo, Kyung-Wook
Cho,
Kim, Do
Kim, Hong
Kim, Young
Woo, Hyun
Kim, Song
Organ, Korean
Paik, Hyo
Park, Seung-Il
Source
PMC
abstract
BACKGROUND: The use of extracorporeal membrane oxygenation (ECMO) as a bridge to lung transplantation has greatly increased. However, data regarding the clinical outcomes of this approach are lacking. The objective of this multicenter prospective observational cohort study was to evaluate lung transplantation outcomes in Korean Organ Transplantation Registry (KOTRY) patients for whom ECMO was used as a bridge to transplantation. METHODS: Between March 2015 and December 2017, a total of 112 patients received lung transplantation and were registered in the KOTRY, which is a prospective, multicenter cohort registry. The entire cohort was divided into two groups: the control group (n = 85, 75.9%) and bridge-ECMO group (n = 27, 24.1%). RESULTS: There were no significant differences in pre-transplant and intraoperative characteristics except for poorer oxygenation, more ventilator use, and longer operation time in the bridge-ECMO group. The prevalence of primary graft dysfunction at 0, 24, 48, and 72 h after transplantation did not differ between the two groups. Although postoperative hospital stays were longer in the bridge-ECMO group than in the control group, hospital mortality did not differ between the two groups (25.9% vs. 13.3%, P = 0.212). The majority of patients (70.4% of the bridge-ECMO group and 77.6% of the control group) were discharged directly to their homes. Finally, the use of ECMO as a bridge to lung transplantation did not significantly affect overall survival and graft function. CONCLUSIONS: Short- and long-term post-transplant outcomes of bridge-ECMO patients were comparable to recipients who did not receive ECMO.
has issue date
2020-01-13
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bibo:doi
10.1186/s12931-020-1289-2
bibo:pmid
31931798
has license
cc-by
sha1sum (hex)
abbdd66a12381ec4e4f3fcb683220a85d2001785
schema:url
https://doi.org/10.1186/s12931-020-1289-2
resource representing a document's title
Extracorporeal membrane oxygenation as a bridge to lung transplantation: analysis of Korean organ transplantation registry (KOTRY) data
has PubMed Central identifier
PMC6958687
has PubMed identifier
31931798
schema:publication
Respir Res
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covid:abbdd66a12381ec4e4f3fcb683220a85d2001785#body_text
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schema:about
of
named entity 'TOTAL'
named entity 'ENTIRE'
named entity 'REGISTRY'
named entity '2015'
named entity 'PROSPECTIVE OBSERVATIONAL COHORT'
named entity 'OBJECTIVE'
named entity 'IS A'
named entity 'control group'
named entity 'ECMO'
named entity 'Extracorporeal membrane oxygenation'
named entity '58.0'
named entity 'hemodynamic support'
named entity 'prognosis'
named entity '11.0'
named entity 'ECMO'
named entity 'end-stage'
named entity 'Idiopathic pulmonary fibrosis'
named entity 'pulmonary function'
named entity 'ECMO'
named entity 'long-term'
named entity 'Eisenmenger syndrome'
named entity 'ECMO'
named entity 'lung disease'
named entity 'functional status'
named entity 'operation time'
named entity 'PGD'
named entity 'ECMO'
named entity 'lung transplantation'
named entity 'follow-up'
named entity 'primary graft dysfunction'
named entity 'rescue therapy'
named entity 'ECMO'
named entity 'interquartile range'
named entity 'hypertension'
named entity 'ventilator-associated pneumonia'
named entity 'infection'
named entity 'ECMO'
named entity 'post-operative'
named entity 'ECMO'
named entity 'long-term'
named entity 'Fisher's exact test'
named entity 'ECMO'
named entity 'lung transplantation'
named entity 'attending physician'
named entity 'ECMO'
named entity 'hemodynamic support'
named entity 'ECMO'
named entity 'ECMO'
named entity 'gas exchange'
named entity 'intraoperative'
named entity 'Pulmonary function'
named entity 'long-term'
named entity 'Kaplan-Meier method'
named entity 'airway'
named entity 'end-stage'
named entity 'lung transplant'
named entity 'critical care'
named entity 'ECMO'
named entity 'FVC'
named entity 'ECMO'
named entity 'primary graft dysfunction'
named entity 'life-threatening'
named entity 'cannulation'
named entity 'lung allocation score'
named entity 'long-term'
named entity 'anticoagulation'
named entity 'lung transplantation'
named entity 'ECMO'
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