About: Zika Virus: What Have We Learnt Since the Start of the Recent Epidemic?

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About: Zika Virus: What Have We Learnt Since the Start of the Recent Epidemic? Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Zika Virus: What Have We Learnt Since the Start of the Recent Epidemic?
Creator	Bueno-Marí, Rubén Heukelbach, Jorg Saiz, Juan-Carlos Mendez-Otero, Rosalia Armstrong, Paul Alencar, Carlos Haider, Abdul-Lateef Lal, Sunil Martín-Acebes, Miguel Mousa, Ortiga-Carvalho, Tania Pimentel-Coelho, Pedro Rosado-De-Castro, Paulo Salomón, Oscar Villamil-Jiménez, Luis Zhao, Xiaopeng Ch, Alencar Lc, Villamil-Jiménez Ma, Martín-Acebes Od, Salomón Pk, Armstrong Saiz, J-C
topic	covid:aba0193185525dbd5c85f38245bcd05861ec4513#this
Source	Medline; PMC
abstract	Zika is a viral disease transmitted mainly by mosquitoes of the genus Aedes. In recent years, it has expanded geographically, changing from an endemic mosquito-borne disease across equatorial Asia and Africa, to an epidemic disease causing large outbreaks in several areas of the world. With the recent Zika virus (ZIKV) outbreaks in the Americas, the disease has become a focus of attention of public health agencies and of the international research community, especially due to an association with neurological disorders in adults and to the severe neurological and ophthalmological abnormalities found in fetuses and newborns of mothers exposed to ZIKV during pregnancy. A large number of studies have been published in the last 3 years, revealing the structure of the virus, how it is transmitted and how it affects human cells. Many different animal models have been developed, which recapitulate several features of ZIKV disease and its neurological consequences. Moreover, several vaccine candidates are now in active preclinical development, and three of them have already entered phase I clinical trials. Likewise, many different compounds targeting viral and cellular components are being tested in in vitro and in experimental animal models. This review aims to discuss the current state of this rapidly growing literature from a multidisciplinary perspective, as well as to present an overview of the public health response to Zika and of the perspectives for the prevention and treatment of this disease.
has issue date	2017-08-22(xsd:dateTime)
bibo:doi	10.3389/fmicb.2017.01554
bibo:pmid	28878742
has license	cc-by
sha1sum (hex)	aba0193185525dbd5c85f38245bcd05861ec4513
schema:url	https://doi.org/10.3389/fmicb.2017.01554
resource representing a document's title	Zika Virus: What Have We Learnt Since the Start of the Recent Epidemic?
has PubMed Central identifier	PMC5572254
has PubMed identifier	28878742
schema:publication	Front Microbiol
resource representing a document's body	covid:aba0193185525dbd5c85f38245bcd05861ec4513#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/aba0193185525dbd5c85f38245bcd05861ec4513
is schema:about of	named entity 'ZIKA VIRUS' named entity 'IN VITRO' named entity 'EXPANDED ' named entity 'PRESENT' named entity 'PUBLIC HEALTH' named entity 'EPIDEMIC DISEASE' named entity 'HUMAN CELLS' named entity 'ACROSS' named entity 'PREVENTION' named entity 'DUE TO' named entity 'DIFFERENT' named entity 'AFRICA' named entity 'DISEASE CAUSING' named entity 'RESEARCH COMMUNITY' named entity 'STRUCTURE' named entity 'VIRAL DISEASE' named entity 'ZIKA' named entity 'IS A' named entity 'VIRUS' named entity 'DISEASE' named entity 'MOSQUITOES' named entity 'OUTBREAKS' named entity 'FEATURES' named entity 'RECENT' named entity 'DEVELOPMENT' named entity 'NEUROLOGICAL DISORDERS' named entity 'NUMBER OF' named entity 'FETUSES' named entity 'ACTIVE' named entity 'ENDEMIC' named entity 'EXPERIMENTAL ANIMAL MODELS' named entity 'INTERNATIONAL' named entity 'outbreaks' named entity 'targeting' named entity 'mosquitoes' named entity 'severe' named entity 'studies' named entity 'rapidly' named entity 'aims' named entity 'Start' named entity 'BORNE' named entity 'OVERVIEW' named entity 'ANIMAL MODELS ' named entity 'WORLD' named entity 'HOW' named entity 'VIRAL AND' named entity 'BEING' named entity 'HEALTH AGENCIES' named entity 'SEVERE' named entity 'AIMS' named entity 'MULTIDISCIPLINARY' named entity 'REVEALING' named entity 'NEUROLOGICAL' named entity 'RAPIDLY' named entity 'DURING PREGNANCY' named entity 'NEWBORNS' named entity 'CONSEQUENCES' named entity 'TARGETING'

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