About: Evaluation of a panel of antibodies for the immunohistochemical identification of immune cells in paraffin-embedded lymphoid tissues of new- and old-world camelids

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Evaluation of a panel of antibodies for the immunohistochemical identification of immune cells in paraffin-embedded lymphoid tissues of new- and old-world camelids Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Evaluation of a panel of antibodies for the immunohistochemical identification of immune cells in paraffin-embedded lymphoid tissues of new- and old-world camelids
Creator	Baumgärtner, Wolfgang Lehmbecker, Annika Uhde, Ann-Kathrin Spitzbarth, Ingo
Source	Elsevier; Medline; PMC
abstract	Different species of camelids play an important role in the epidemiology of various emerging infectious diseases such as Middle East respiratory syndrome. For precise investigations of the immunopathogenesis in these host species, appropriate immunohistochemical markers are highly needed in order to phenotype distinct immune cells populations in camelids. So far, specific immunohistochemical markers for camelid immune cells are rarely commercially available, and cross-reactivity studies are restricted to the use of frozen dromedary tissues. To bridge this gap, 14 commercially available primary antibodies were tested for their suitability to demonstrate immune cell populations on formalin fixed paraffin-embedded (FFPE) tissue sections of dromedaries, Bactrian camels, llamas, and alpacas in the present study. Out of these, 9 antibodies directed against CD3, CD20, CD79α, HLA-DR, Iba-1, myeloid/histiocyte antigen, CD204, CD208, and CD68 antigen exhibited distinct immunoreaction patterns to certain camelid immune cell subsets. The distribution of these antigens was comparatively evaluated in different anatomical compartments of thymus, spleen, mesenteric, and tracheobronchial lymph nodes. The presented results will provide a basis for further investigations in camelids, especially with respect to the role of the immune response in certain infectious diseases, which harbor a considerable risk to spill over to other species.
has issue date	2017-01-17(xsd:dateTime)
bibo:doi	10.1016/j.vetimm.2017.01.001
bibo:pmid	28166931
has license	no-cc
sha1sum (hex)	aa2adeef4580700fb57919c3184488f569f5f184
schema:url	https://doi.org/10.1016/j.vetimm.2017.01.001
resource representing a document's title	Evaluation of a panel of antibodies for the immunohistochemical identification of immune cells in paraffin-embedded lymphoid tissues of new- and old-world camelids
has PubMed Central identifier	PMC7111308
has PubMed identifier	28166931
schema:publication	Vet Immunol Immunopathol
resource representing a document's body	covid:aa2adeef4580700fb57919c3184488f569f5f184#body_text
is schema:about of	named entity 'immune cell' named entity 'CD20' named entity 'sections' named entity 'antibodies' named entity 'camelids' named entity 'PARAFFIN-EMBEDDED' named entity 'NEW' named entity 'RESPECT' named entity 'DROMEDARY' named entity 'SPECIFIC' named entity 'CAMELS' named entity 'PATTERNS' named entity 'MIDDLE EAST RESPIRATORY SYNDROME' named entity 'WORLD' named entity 'RESTRICTED' named entity 'REACTIVITY' named entity 'FROZEN' named entity 'PRESENT' named entity 'THEIR' named entity 'ANTIGEN' named entity 'CD208' named entity 'TISSUES' named entity 'TISSUE' named entity 'ALPACAS' named entity 'IMMUNE RESPONSE' named entity 'PRIMARY' named entity 'IMMUNOPATHOGENESIS' named entity 'PROVIDE' named entity 'EMERGING INFECTIOUS DISEASES' named entity 'RESULTS' named entity 'ORDER' named entity 'EPIDEMIOLOGY' named entity 'FORMALIN' named entity 'IMMUNE CELL' named entity 'HOST SPECIES' named entity 'ANATOMICAL' named entity 'ANTIGENS' named entity 'CD68 ANTIGEN' named entity 'CD204' named entity 'OLD' named entity 'EVALUATION' named entity 'CERTAIN' named entity 'IMPORTANT' named entity 'CD79' named entity 'CONSIDERABLE' named entity 'IMMUNOREACTION' named entity 'POPULATIONS' named entity 'GAP' named entity 'IMMUNE CELLS' named entity 'PANEL' named entity 'MARKERS' named entity 'RISK' named entity 'SPILL' named entity 'LLAMAS' named entity 'RARELY' named entity 'APPROPRIATE' named entity 'EVALUATED' named entity 'PLAY' named entity 'ANTIBODIES' named entity 'THESE' named entity 'VARIOUS' named entity 'IBA' named entity 'DISTRIBUTION' named entity 'LYMPHOID TISSUES' named entity 'IDENTIFICATION' named entity 'STUDIES' named entity 'MYELOID' named entity 'CROSS' named entity 'TRACHEOBRONCHIAL LYMPH NODES' named entity 'ROLE' named entity 'DIRECTED' named entity 'INFECTIOUS DISEASES' named entity 'DIFFERENT' named entity 'SPLEEN' named entity 'THYMUS' named entity 'PARAFFIN-EMBEDDED' named entity 'CD20' named entity 'COMPARTMENTS'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software