About: High-Dose Corticosteroid Use and Risk of Hip Osteonecrosis: Meta-Analysis and Systematic Literature Review

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About: High-Dose Corticosteroid Use and Risk of Hip Osteonecrosis: Meta-Analysis and Systematic Literature Review Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	High-Dose Corticosteroid Use and Risk of Hip Osteonecrosis: Meta-Analysis and Systematic Literature Review
Creator	Banerjee, Samik Pivec, Robert Elmallah, Randa Jones, Lynne Mont, Michael
Source	Elsevier; Medline; PMC
abstract	Abstract The effect of varying corticosteroid regimens on hip osteonecrosis incidence remains unclear. We performed a meta-analysis and systematic literature review to determine osteonecrosis occurrences in patients taking corticosteroids at varying mean and cumulative doses and treatment durations, and whether medical diagnoses affected osteonecrosis incidence. Fifty-seven studies (23,561 patients) were reviewed. Regression analysis determined significance between corticosteroid usage and osteonecrosis incidence. Osteonecrosis incidence was 6.7% with corticosteroid treatment of >2 g (prednisone-equivalent). Systemic lupus erythematosus patients had positive correlations between dose and osteonecrosis incidence. Each 10 mg/d increase was associated with a 3.6% increase in osteonecrosis rate, and >20 mg/d resulted in a higher osteonecrosis incidence. Clinicians must be wary of osteonecrosis in patients on high corticosteroid regimens, particularly in systematic lupus erythematosus.
has issue date	2015-09-30(xsd:dateTime)
bibo:doi	10.1016/j.arth.2015.03.036
bibo:pmid	25900167
has license	els-covid
sha1sum (hex)	a8a3cc7f31b73040096c07b52a382cf0b2b40cdc
schema:url	https://doi.org/10.1016/j.arth.2015.03.036
resource representing a document's title	High-Dose Corticosteroid Use and Risk of Hip Osteonecrosis: Meta-Analysis and Systematic Literature Review
has PubMed Central identifier	PMC7127809
has PubMed identifier	25900167
schema:publication	The Journal of Arthroplasty
resource representing a document's body	covid:a8a3cc7f31b73040096c07b52a382cf0b2b40cdc#body_text
is schema:about of	named entity 'RISK OF' named entity 'HIP' named entity 'CORTICOSTEROID' named entity 'OSTEONECROSIS' named entity 'HIP' named entity 'LITERATURE REVIEW' named entity 'META-ANALYSIS' named entity 'META-ANALYSIS' named entity 'CORTICOSTEROID USE' named entity 'HIGH-DOSE' named entity 'OSTEONECROSIS' named entity 'RISK FACTORS' named entity 'KEYWORDS' covid:arg/a8a3cc7f31b73040096c07b52a382cf0b2b40cdc named entity 'corticosteroid' named entity 'meta-analysis' named entity 'High-Dose' named entity 'Meta-Analysis' named entity 'medical diagnoses' named entity 'case-control studies' named entity 'synergistic' named entity 'osteonecrosis' named entity 'literature search' named entity 'meta-analysis' named entity 'renal transplantation' named entity 'osteonecrosis' named entity 'autoimmune diseases' named entity 'osteonecrosis' named entity 'random effects model' named entity 'osteonecrosis' named entity 'osteonecrosis' named entity 'corticosteroid' named entity 'bone marrow transplantation' named entity 'systematic review' named entity 'osteonecrosis' named entity 'osteonecrosis' named entity 'osteonecrosis' named entity 'renal transplant' named entity 'dermatologic' named entity 'corticosteroid' named entity 'publication bias' named entity 'case series' named entity 'renal transplantation' named entity 'liver transplantation' named entity 'Armonk' named entity 'osteonecrosis' named entity 'dose-response relationships' named entity 'osteonecrosis' named entity 'SLE' named entity 'corticosteroid' named entity 'SLE' named entity 'corticosteroids' named entity 'renal transplantation' named entity 'corticosteroids' named entity 'idiopathic' named entity 'potencies' named entity 'MRI' named entity 'renal transplant' named entity 'dependent variable' named entity 'osteonecrosis' named entity 'SLE' named entity 'corticosteroids' named entity 'corticosteroids' named entity 'confidence interval' named entity 'corticosteroid' named entity 'corticosteroid' named entity 'Microsoft Corporation' named entity 'R-square' named entity 'synergistic' named entity 'MRI' named entity 'corticosteroid' named entity 'reporting bias' named entity 'osteonecrosis' named entity 'Asian' named entity 'corticosteroids' named entity 'SLE' named entity 'organ transplant'

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