About: High Community SARS-CoV-2 Antibody Seroprevalence in a Ski Resort Community, Blaine County, Idaho, US. Preliminary Results

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About: High Community SARS-CoV-2 Antibody Seroprevalence in a Ski Resort Community, Blaine County, Idaho, US. Preliminary Results Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	High Community SARS-CoV-2 Antibody Seroprevalence in a Ski Resort Community, Blaine County, Idaho, US. Preliminary Results
Creator	Corey, Lawrence Jerome, Keith Bossard, Emily Diem, Kurt Doll, Margaret Ford, Emily Klock, Alexis Morrison, Kathryn Phasouk, Khamsone Sholukh, Anton Mclaughlin, Colleen Mclaughlin, William O'connor, Terry
source	MedRxiv; Medline; PMC
abstract	Community-level seroprevalence surveys are needed to determine the proportion of the population with previous SARS-CoV-2 infection, a necessary component of COVID-19 disease surveillance. In May, 2020, we conducted a cross-sectional seroprevalence study of IgG antibodies for nucleocapsid of SARS-CoV-2 among the residents of Blaine County, Idaho, a ski resort community with high COVID-19 attack rates in late March and Early April (2.9% for ages 18 and older). Participants were selected from volunteers who registered via a secure web link, using prestratification weighting to the population distribution by age and gender within each ZIP Code. Participants completed a survey reporting their demographics and symptoms; 88% of volunteers who were invited to participate completed data collection survey and had 10 ml of blood drawn. Serology was completed via the Abbott Architect SARS-CoV-2 IgG immunoassay. Primary analyses estimated seroprevalence and 95% credible intervals (CI) using a hierarchical Bayesian framework to account for diagnostic uncertainty. Stratified models were run by age, sex, ZIP Code, ethnicity, employment status, and a priori participant-reported COVID-19 status. Sensitivity analyses to estimate seroprevalence included base models with post-stratification for ethnicity, age, and sex, with or without adjustment for multi-participant households. IgG antibodies to the virus that causes COVID-19 were found among 22.7% (95% CI: 20.1%, 25.5%) of residents of Blaine County. Higher levels of antibodies were found among residents of the City of Ketchum 34.8% (95% CI 29.3%, 40.5%), compared to Hailey 16.8% (95%CI 13.7%, 20.3%) and Sun Valley 19.4% (95% 11.8%, 28.4%). People who self-identified as not believing they had COVID-19 had the lowest prevalence 4.8% (95% CI 2.3%, 8.2%). The range of seroprevalence after correction for potential selection bias was 21.9% to 24.2%. This study suggests more than 80% of SARS-CoV-2 infections were not reported. Although Blaine County had high levels of SARS-CoV-2 infection, the community is not yet near the herd immunity threshold.
has issue date	2020-07-21(xsd:dateTime)
bibo:doi	10.1101/2020.07.19.20157198
bibo:pmid	32743610
has license	cc-by-nc-nd
sha1sum (hex)	a88636f688d2bd28de31b7daf8f7ce00ca40362d
schema:url	https://doi.org/10.1101/2020.07.19.20157198
resource representing a document's title	High Community SARS-CoV-2 Antibody Seroprevalence in a Ski Resort Community, Blaine County, Idaho, US. Preliminary Results
has PubMed Central identifier	PMC7386534
has PubMed identifier	32743610
schema:publication	medRxiv
resource representing a document's body	covid:a88636f688d2bd28de31b7daf8f7ce00ca40362d#body_text
is schema:about of	named entity 'high' named entity 'Architect' named entity 'volunteers' named entity 'Blaine County, Idaho' named entity 'data collection' named entity 'population' named entity 'ages' named entity 'survey' named entity 'SARS-CoV-2' named entity 'invited' named entity 'IgG' named entity 'COVID-19' named entity 'needed' named entity 'In May' named entity 'SARS-CoV-2' named entity 'seroprevalence' named entity 'Blaine County, Idaho' named entity 'SARS-CoV-2' named entity 'Serology' named entity 'IgG' named entity 'COVID' named entity 'Seroprevalence' named entity 'COVID-19' named entity 'COVID' named entity 'cumulative incidence' named entity 'coronavirus' named entity 'SARS-CoV-2' named entity 'peer review' named entity 'Blaine County' named entity 'U.S.' named entity 'seroprevalence' named entity 'seroprevalence' named entity 'Blaine County' named entity 'peer review' named entity 'questionnaire' named entity 'credible intervals' named entity 'infection' named entity 'population demographics' named entity 'public health surveillance' named entity 'June 2020' named entity 'medical professional' named entity 'herd immunity' named entity 'nucleocapsid' named entity 'University of Washington' named entity 'seroprevalence' named entity 'medRxiv' named entity 'antibody testing' named entity 'Blaine County' named entity 'Stratified models' named entity 'seroprevalence' named entity 'IgG' named entity 'medRxiv' named entity 'immunoassay' named entity 'cumulative incidence' named entity 'sensitivity and specificity' named entity 'centrifugation' named entity 'medRxiv' named entity 'Blaine County' named entity 'dextrose' named entity 'Sun Valley Resort' named entity 'infection' named entity 'SARS-CoV-2' named entity 'COVID' named entity 'seroprevalence' named entity 'selection bias' named entity 'medical diagnosis' named entity 'COVID' named entity 'ethnicity' named entity 'May 19'

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