About: Management of bilateral uveitis in a Toxoplasma gondii‐seropositive cat with histopathologic evidence of fungal panuveitis

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About: Management of bilateral uveitis in a Toxoplasma gondii‐seropositive cat with histopathologic evidence of fungal panuveitis Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Management of bilateral uveitis in a Toxoplasma gondii‐seropositive cat with histopathologic evidence of fungal panuveitis
Creator	Galle, L Giuliano, E Giuliano, Elizabeth Klauss, G Moore, C Ota, J Pearce, J
Source	Medline; PMC
abstract	A 5‐year‐old, neutered male Domestic Short‐haired cat was referred with a 5‐month history of anterior uveitis and cataract in the right eye. Clinical examination confirmed anterior uveitis and immature cataract in the right eye and chorioretinitis in the left eye. Ocular ultrasound showed a retinal detachment in the right eye. Diagnostic testing revealed elevated serum titers for Toxoplasma gondii. Anterior uveitis in the right eye and chorioretinitis in the left eye progressed, resulting in blindness despite a 21‐day course of clindamycin and aggressive topical medical management of uveitis. The right eye was enucleated and histopathologic evaluation of the globe revealed panuveitis and multiple organisms morphologically consistent with Histoplasma capsulatum. Systemic treatment with itraconazole was initiated. Vision returned after 3 months of treatment and complete resolution of the retinal hemorrhages with formation of a flat chorioretinal scar was noted after 6 months of therapy. Itraconazole was discontinued 7 months after starting therapy, at which time the funduscopic appearance of the chorioretinal scar had remained static for 1 month. The cat has remained visual without evidence of disease progression for 6 months following discontinuation of itraconazole.
has issue date	2007-06-11(xsd:dateTime)
bibo:doi	10.1111/j.1463-5224.2007.00541.x
bibo:pmid	17565553
has license	no-cc
sha1sum (hex)	a87bdfe1b7a8b5c9c4bc2f6e39518c7bfad2a93f
schema:url	https://doi.org/10.1111/j.1463-5224.2007.00541.x
resource representing a document's title	Management of bilateral uveitis in a Toxoplasma gondii‐seropositive cat with histopathologic evidence of fungal panuveitis
has PubMed Central identifier	PMC7169290
has PubMed identifier	17565553
schema:publication	Vet Ophthalmol
resource representing a document's body	covid:a87bdfe1b7a8b5c9c4bc2f6e39518c7bfad2a93f#body_text
is schema:about of	named entity 'discontinued' named entity 'hemorrhages' named entity 'day' named entity 'cataract' named entity 'visual' named entity 'eye' named entity 'A 5' named entity 'fungal' named entity 'HISTOPLASMA CAPSULATUM' named entity 'AGGRESSIVE' named entity 'CLINDAMYCIN' named entity 'MONTHS' named entity 'EVIDENCE OF' named entity 'APPEARANCE' named entity 'RETINAL HEMORRHAGES' named entity 'RETURNED' named entity 'THERAPY' named entity 'CHORIORETINITIS' named entity 'CONFIRMED' named entity 'CAT' named entity 'CHORIORETINAL SCAR' named entity 'neutered' named entity 'retinal' named entity 'scar' named entity 'complete' named entity 'uveitis' named entity 'The' named entity 'left eye' named entity 'scar' named entity 'cataract' named entity 'blindness' named entity 'serum' named entity 'Histoplasma capsulatum' named entity 'Toxoplasma gondii' named entity 'chorioretinal' named entity 'scar' named entity 'Diagnostic testing' named entity 'cataract' named entity 'Clinical examination' named entity 'anterior uveitis' named entity 'panuveitis' named entity 'ultrasound' named entity 'eye' named entity 'morphologically' named entity 'Neuro-ophthalmic' named entity 'aqueous flare' named entity 'organism' named entity 'USP' named entity 'lymphopenia' named entity 'lungs' named entity 'T. gondii' named entity 'anti-inflammatory medications' named entity 'ointment' named entity 'H. capsulatum' named entity 'T. gondii' named entity 'slit-lamp' named entity 'azole' named entity 'pigmented cells' named entity 'alkaline phosphatase' named entity 'Toxoplasma' named entity 'itraconazole' named entity 'parasitism' named entity 'experimental subjects' named entity 'uveitis' named entity 'Allergan Inc.' named entity 'ocular disease' named entity '21 days' named entity 'cornea' named entity 'Irvine, CA' named entity 'antigen' named entity 'silver stains' named entity 'Idexx Laboratories' named entity 'serologic tests' named entity 'idiopathic' named entity 'immune-mediated'

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