About: The Midwest ST-Elevation Myocardial Infarction Consortium: Design and Rationale

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The Midwest ST-Elevation Myocardial Infarction Consortium: Design and Rationale
Creator	Schmidt, Christian Henry, Timothy Aguirre, Frank Chambers Mba, Jenny Chambers, Jenny Coulson, Teresa Garberich, Ross Garcia, Santiago Pacheco-Coronado, Roberto Rohm, Heather Sharkey, Scott Shivapour, Daniel Smith, Timothy Tannenbaum, Mark Yildiz, Mehmet
Source	Elsevier; PMC
abstract	Abstract Background Over the past 20 years, the development of regional ST-elevation myocardial infarction (STEMI) care systems has led to remarkable progress in achieving timely coronary reperfusion with attendant improvement in clinical outcomes, including survival. Despite this progress, contemporary STEMI care does not consistently meet the national guideline-recommended goals, which offers an opportunity for further improvement in STEMI outcomes. The lack of single, comprehensive, national STEMI registry complicates our ability to improve STEMI outcomes in particular for high-risk STEMI subsets such as cardiac arrest (CA) and/or cardiogenic shock (CS). Objectives To address this need, the Midwest STEMI Consortium (MSC) was created as a collaboration of 4 large, regional STEMI care systems to provide a comprehensive, multicenter, and prospective STEMI registry without any exclusionary criteria. Methods The MSC is a collaboration of 4 large, regional STEMI care systems: Iowa Heart Center in Des Moines, IA; Minneapolis Heart Institute Foundation in Minneapolis, MN; Prairie Heart Institute in Springfield, IL; and The Christ Hospital in Cincinnati, OH. Each has similar standardized STEMI protocol and together include 6 percutaneous coronary intervention (PCI)-capable hospitals and over 100 non-PCI-capable hospitals. Each center had a prospective database that was transferred to a data coordinating center to create the multicenter database. The comprehensive database includes traditional risk factors, cardiovascular history, medications, time to treatment data, detailed angiographic characteristics, and short- and long-term clinical outcomes up to 5-year for myocardial infarction, stroke, and cardiovascular and all-cause mortality. Ten-year mortality rates were assessed by using national death index. Results Currently, the comprehensive database (03/2003-01/2020) includes 14,911 consecutive STEMI patients with mean age of 62.3 ± 13.6 years, female gender (29%), and left anterior descending artery as the culprit vessel (34%). High risk features included: Age >75 years (19%), left ventricular ejection fraction <35% (15%), CA (10%), and CS (8%). Conclusion This collaboration of 4 large, regional STEMI care systems with broad entry criteria including high-risk STEMI subsets such as CA and/or CS provides a unique platform to conduct clinical research studies to optimize STEMI care.
has issue date	2020-08-13(xsd:dateTime)
bibo:doi	10.1016/j.carrev.2020.08.019
has license	els-covid
sha1sum (hex)	a84bc56e9cf83245e2c4d969647c576947d12567
schema:url	https://doi.org/10.1016/j.carrev.2020.08.019
resource representing a document's title	The Midwest ST-Elevation Myocardial Infarction Consortium: Design and Rationale
has PubMed Central identifier	PMC7425714
schema:publication	Cardiovascular Revascularization Medicine
resource representing a document's body	covid:a84bc56e9cf83245e2c4d969647c576947d12567#body_text
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