About: Incidence, Risk Factors, and Outcomes of Ventilator-Associated Pneumonia in Traumatic Brain Injury: A Meta-analysis

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About: Incidence, Risk Factors, and Outcomes of Ventilator-Associated Pneumonia in Traumatic Brain Injury: A Meta-analysis Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Incidence, Risk Factors, and Outcomes of Ventilator-Associated Pneumonia in Traumatic Brain Injury: A Meta-analysis
Creator	Xiao, Wei Li, Yating Liu, Chenxia Song, Tiantian Wang, Shuhui
Source	PMC
abstract	Ventilator-associated pneumonia (VAP) is one of the most severe complications in patients with traumatic brain injury (TBI) and is considered a risk factor for poor outcomes. However, the incidence of VAP among patients with TBI reported in studies varies widely. What is more, the risk factors and outcomes of VAP are controversial. This study estimates the incidence, risk factors, and outcomes of VAP in patients with TBI and provides evidence for prevention and treatment. PubMed, EMBASE, Cochrane Library, and Web of Science databases were searched from the earliest records to May 2018. Data involving the incidence, risk factors, and outcomes were extracted for meta-analysis. The results showed that the incidence of VAP was 36% (95% confidence interval (CI) 31–41%); risk factors analyses showed that smoking [odds ratio (OR) 2.13; 95% CI 1.16–3.92], tracheostomy (OR 9.55; 95% CI 3.24–28.17), blood transfusion on admission (OR 2.54; 95% CI 1.24–5.18), barbiturate infusion (OR 3.52; 95% CI 1.68–7.40), injury severity score (OR 4.65; 95% CI 1.96–7.34), and head abbreviated injury scale (OR 2.99; 95% CI 1.66–5.37) were related to the occurrence of VAP. When patients developed VAP, mechanical ventilation time (OR 5.45; 95% CI 3.78–7.12), ICU length of stay (OR 6.85; 95% CI 4.90–8.79), and hospital length of stay (OR 10.92; 95% CI 9.12–12.72) were significantly increased. However, VAP was not associated with an increased risk of mortality (OR 1.28; 95% CI 0.74–2.21). VAP is common in patients with TBI. It is affected by a series of factors and has a poor prognosis. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s12028-019-00773-w) contains supplementary material, which is available to authorized users.
has issue date	2019-07-12(xsd:dateTime)
bibo:doi	10.1007/s12028-019-00773-w
bibo:pmid	31300956
has license	no-cc
sha1sum (hex)	a79135fc22955a78f8756c6cbb78764e72d0d640
schema:url	https://doi.org/10.1007/s12028-019-00773-w
resource representing a document's title	Incidence, Risk Factors, and Outcomes of Ventilator-Associated Pneumonia in Traumatic Brain Injury: A Meta-analysis
has PubMed Central identifier	PMC7223912
has PubMed identifier	31300956
schema:publication	Neurocrit Care
resource representing a document's body	covid:a79135fc22955a78f8756c6cbb78764e72d0d640#body_text
is schema:about of	named entity 'injury severity score' named entity 'patients' named entity 'patients' named entity 'EMBASE' named entity 'extracted' named entity 'Meta-analysis' named entity 'Outcomes' named entity 'traumatic brain injury (TBI)' named entity 'TBI' named entity 'series' named entity 'study' named entity 'estimates' named entity 'patients' named entity 'smoking' named entity 'risk factors' named entity 'VAP' named entity 'VAP' named entity 'meta-analysis' named entity 'microbiological' named entity 'prophylactic antibiotics' named entity '95% CI' named entity 'Asia' named entity 'Web' named entity '95% CI' named entity 'Data' named entity 'VAP' named entity 'abbreviated injury scale' named entity 'odds ratio' named entity 'TBI' named entity '95% CI' named entity 'VAP' named entity 'tracheostomy' named entity '95% CI' named entity 'TBI' named entity 'ICU' named entity 'Ventilator-Associated Pneumonia' named entity 'Traumatic Brain Injury' named entity 'CDC' named entity 'VAP' named entity 'tracheotomy' named entity 'VAP' named entity 'meta-analysis' named entity 'North America' named entity 'trauma patients' named entity 'respiratory tract' named entity 'VAP' named entity 'mechanical ventilation' named entity 'VAP' named entity 'risk factors' named entity 'VAP' named entity 'literature search' named entity 'North American' named entity 'severe trauma' named entity 'immunosuppressive' named entity 'VAP' named entity 'risk factor' named entity 'VAP' named entity 'VAP' named entity 'GCS' named entity 'missing data' named entity 'AIS' named entity 'inflammatory response' named entity 'Web of Science' named entity 'subgroup analyses' named entity 'VAP' named entity 'publication bias' named entity 'VAP' named entity 'Europe' named entity 'transfusion of blood' named entity 'barbiturate' named entity 'TBI' named entity 'prophylactic antibiotics' named entity 'consciousness' named entity 'pneumonia' named entity 'brain injury' named entity 'mechanical ventilation' named entity 'TBI'

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