About: Feline and canine coronaviruses are released from the basolateral side of polarized epithelial LLC-PK1 cells expressing the recombinant feline aminopeptidase-N cDNA

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About: Feline and canine coronaviruses are released from the basolateral side of polarized epithelial LLC-PK1 cells expressing the recombinant feline aminopeptidase-N cDNA Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Feline and canine coronaviruses are released from the basolateral side of polarized epithelial LLC-PK1 cells expressing the recombinant feline aminopeptidase-N cDNA
Creator	Vennema, H Rottier, P Goedheer, A Kouame, J Rossen, J
source	Medline; PMC
abstract	In this study feline (FECV and FIPV) and canine (CCoV) coronavirus entry into and release from polarized porcine epithelial LLC-PK1 cells, stably expressing the recombinant feline aminopeptidase-N cDNA, were investigated. Virus entry appeared to occur preferentially through the apical membrane, similar to the entry of the related porcine coronavirus transmissible gastroenteritis virus (TGEV) into these cells. However, whereas TGEV is released apically, feline and canine coronaviruses were found to be released from the basolateral side of the epithelial cells. These observations indicate that local infections as caused by TGEV, FECV and CCoV do not strictly correlate with apical release, as suggested by earlier work.
has issue date	2001-01-01(xsd:dateTime)
bibo:doi	10.1007/s007050170147
bibo:pmid	11402864
has license	no-cc
sha1sum (hex)	a632d08f54beeb339515d06fda9d2bb47d703b3f
schema:url	https://doi.org/10.1007/s007050170147
resource representing a document's title	Feline and canine coronaviruses are released from the basolateral side of polarized epithelial LLC-PK1 cells expressing the recombinant feline aminopeptidase-N cDNA
has PubMed Central identifier	PMC7087204
has PubMed identifier	11402864
schema:publication	Arch Virol
resource representing a document's body	covid:a632d08f54beeb339515d06fda9d2bb47d703b3f#body_text
is schema:about of	named entity 'respiratory' named entity 'cells' named entity 'feline' named entity 'side' named entity 'released' »more»

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