About: Is a 14-day quarantine period optimal for effectively controlling coronavirus disease 2019 (COVID-19)?

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Is a 14-day quarantine period optimal for effectively controlling coronavirus disease 2019 (COVID-19)? Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Is a 14-day quarantine period optimal for effectively controlling coronavirus disease 2019 (COVID-19)?
Creator	Li, Lin Liao, Bo Li, Xiong Cai, Wenxiang Chen, Yucan Jiang, Xue Niu, Yawei Wang, Edwin
Source	MedRxiv
abstract	Background The outbreak of a new coronavirus (SARS-CoV-2) disease (Covid-19) has become pandemic. To be more effectively controlling the disease, it is critical to set up an optimal quarantine period so that about 95% of the cases developing symptoms will be retained for isolation. At the moment, the WHO-established quarantine period is 14 days based on previous reports which had studied small sizes of hospitalized cases (10 and ~100, respectively), however, over 80% of adult- and 95% of child-cases were not necessary to stay in hospitals, and therefore, had not been hospitalized. Therefore, we are questioning if the current-inferred median incubation time is representative for the whole Covid-19 population, and if the current quarantine period is optimal. Methods We compiled and analyzed the patient-level information of 2015 laboratory-confirmed Covid-19 cases including 99 children in 28 Chinese provinces. This cohort represents a wide-range spectrum of Covid-19 disease with both hospitalized and non-hospitalized cases. Results The full range of incubation periods of the Covid-19 cases ranged from 0 to 33 days among 2015 cases. There were 6 (0.13%) symptom-free cases including 4 females with a median age of 25.5 years and 2 males with a median age of 36 years. The median incubation period of both male and female adults was similar (7-day) but significantly shorter than that (9-day) of child cases (P=0.02). This cohort contained 4 transmission generations, and incubation periods of the cases between generations were not significantly different, suggesting that the virus has not been rapidly adapted to human beings. Interestingly, incubation periods of 233 cases (11.6%) were longer than the WHO-established quarantine period (14 days). Data modeling suggested that if adults take an extra 4-day or 7-day of isolation (i.e., a quarantine period of 18 or 21 days), 96.2% or 98.3%, respectively, of the people who are developing symptoms will be more effectively quarantined. Patients transmitted via lunch/dinner parties (i.e., gastrointestinal tract infection through oral transmission) had a significantly longer incubation period (9-day) than other adults transmitted via respiratory droplets or contaminated surfaces and objects (P<0.004). Conclusions The whole Covid-19 population including both hospitalized and non-hospitalized cases had a median incubation period of 7-day for adults, which is 1.8-day longer than the hospitalized cases reported previously. An extension of the adult quarantine period to 18 days or 21 days could be more effective in preventing virus-spreading and controlling the disease. The cases transmitted by lunch/dinner parties could be infected first in the gastrointestinal tract through oral transmission and then infected in the respiratory system so that they had a longer incubation period.
has issue date	2020-03-18(xsd:dateTime)
bibo:doi	10.1101/2020.03.15.20036533
has license	medrxiv
sha1sum (hex)	a6203f5bc0f1ac39f4c722a6d9aa6918858f5de1
schema:url	https://doi.org/10.1101/2020.03.15.20036533
resource representing a document's title	Is a 14-day quarantine period optimal for effectively controlling coronavirus disease 2019 (COVID-19)?
resource representing a document's body	covid:a6203f5bc0f1ac39f4c722a6d9aa6918858f5de1#body_text
is schema:about of	named entity 'sizes' named entity 'OUTBREAK' covid:arg/a6203f5bc0f1ac39f4c722a6d9aa6918858f5de1 named entity 'SARS-CoV-2' named entity 'controlling' named entity 'coronavirus' named entity 'SARS-CoV-2' named entity 'preprint' named entity 'medRxiv' named entity 'WHO' named entity 'nausea' named entity 'sample size' named entity 'preprint' named entity 'CC-BY-NC 4.0' named entity 'incubation period' named entity '21 days' named entity 'Covid' named entity 'quarantine' named entity 'Hubei' named entity 'quarantine' named entity 'respiratory symptoms' named entity 'diarrhea' named entity 'foodsharing' named entity 'quarantine' named entity 'infection' named entity 'incubation period' named entity 'contact tracing' named entity 'Hubei' named entity 'incubation period' named entity 'case reports' named entity 'free software' named entity 'gastrointestinal tract' named entity 'demographic information' named entity 'deidentified' named entity 'incubation time' named entity 'quarantine' named entity 'Wuhan' named entity 'China' named entity 'virus' named entity 'diarrhea' named entity 'preprint' named entity 'coronavirus' named entity 'public health interventions' named entity 'virus' named entity 'medRxiv' named entity 'case reports' named entity 'health intervention' named entity 'shedding virus' named entity 'incubation period' named entity 'SARS-CoV-2' named entity 'symptom' named entity 'fever' named entity 'preprint' named entity 'quarantine' named entity 'peer review' named entity 'SARS-CoV-2' named entity '21 days' named entity 'contaminated surfaces' named entity 'Covid-19' named entity 'Covid' named entity 'statistical analysis' named entity 'public health' named entity 'preprint' named entity 'virus' named entity 'fecal-oral transmission' named entity 'SARS' named entity 'preprint' named entity 'data analysis' named entity 'SARS-CoV-2' named entity 'incubation time' named entity 'curate' named entity 'social distancing' named entity 'preprint' named entity 'SARS-CoV-2' named entity 'medRxiv' named entity 'peer review' named entity 'Wuhan' named entity 'preprint'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software