About: Epidemiologic and clinical characteristics of 10 children with coronavirus disease 2019 in Changsha, China

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Epidemiologic and clinical characteristics of 10 children with coronavirus disease 2019 in Changsha, China
Creator	Wu, Jing Pan, Jia Zeng, Sai-Zhen Tan, Bo-Yu Tan, Yu-Pin Wei, Hong-Yan
Source	Elsevier; Medline; PMC
abstract	BACKGROUND: The outbreak of a new coronavirus, first reported in Wuhan, China, is spreading around the world. Information on the characteristics of children with Coronavirus Disease 2019 (COVID-19) is limited. METHODS: In this retrospective study, we recruited 10 children infected with SARS-COV-2 from January 27 to March 10, 2020, in Changsha, China. We report the epidemiological, clinical, laboratory, and high-resolution CT findings for these children. Qualitative descriptive analysis was used to describe the key results. RESULTS: Ten children were included. Three were male and seven were female. Three were from Wuhan, Hubei Province, and seven were from Changsha. All had a history of close contact with adults with COVID-19 before the onset of disease. Clinical manifestations included fever in four cases, respiratory symptoms in three cases, febrile convulsions in one case, vomiting in one case, abdominal pain in one case, and asymptomatic infection in two cases. All the children tested positive for nucleic acid in throat swabs at admission. Stool swabs of three cases were positive for nucleic acid after several days of fever. In nine children, blood routine results were normal, whereas in one case the white blood cell count was elevated. In four cases, CT findings of the lungs showed light ground-glass opacities, one case showed changes similar to bronchopneumonia, and the remaining cases were normal. All were treated with symptomatic support without complications. CONCLUSION: Our findings indicate that intrafamily transmission may be the main form of transmission of COVID-19 in children, and persistent intestinal excretion of virus is another characteristic among children. The results of stool swab tests should be considered for discharge and release from isolation.
has issue date	2020-04-10(xsd:dateTime)
bibo:doi	10.1016/j.jcv.2020.104353
bibo:pmid	32302953
has license	no-cc
sha1sum (hex)	a53d30adbd13d943afa8fe9bcd6b92bd794f0dd7
schema:url	https://doi.org/10.1016/j.jcv.2020.104353
resource representing a document's title	Epidemiologic and clinical characteristics of 10 children with coronavirus disease 2019 in Changsha, China
has PubMed Central identifier	PMC7195108
has PubMed identifier	32302953
schema:publication	J Clin Virol
resource representing a document's body	covid:a53d30adbd13d943afa8fe9bcd6b92bd794f0dd7#body_text
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