About: Predictors and outcome of patients with acute respiratory distress syndrome caused by miliary tuberculosis: a retrospective study in Chongqing, China

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About: Predictors and outcome of patients with acute respiratory distress syndrome caused by miliary tuberculosis: a retrospective study in Chongqing, China Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Predictors and outcome of patients with acute respiratory distress syndrome caused by miliary tuberculosis: a retrospective study in Chongqing, China
Creator	Chen, Gang Wang, Yong Hu, Liang Yu, Min Tong, Jin Deng, Wang Deng, Jia Li, Changyi Ma, Hilary Wang, Dao
Source	PMC
abstract	BACKGROUND: Miliary tuberculosis (TB) is an uncommon cause of acute respiratory distress syndrome (ARDS) with a high mortality. The aim of the present study was to evaluate the clinical characteristics, predictors and outcome of patients with ARDS caused by miliary TB. METHODS: A retrospective study was conducted among patients with a diagnosis of ARDS with miliary TB in four hospitals from 2006 to 2010. Medical records and laboratory examinations of these patients were taken during the first 24 h of admission. RESULTS: Eighty-five patients with miliary TB developed ARDS, 45 of whom survived (52.9%). The median age was 36.6 ± 12.5 years with 38 males (44.7%). Diabetes mellitus (DM) was the most common underlying disease (18.8%).ICU mortality was 47.1%. The time from admission to anti-tuberculosis therapy was 4.5 ± 2.0 days. Mean duration of mechanical ventilation was 8.5 ± 3.0 days in all patients. Duration of time to diagnosis, time from diagnosis to mechanical ventilation, and time to anti-tuberculosis therapy were significantly shorter in survivors than those in non-survivors. Diabetes mellitus (OR 5.431, 95%CI 1.471-20.049; P = 0.005), ALT (70-100U/L, OR 10.029, 95%CI 2.764-36.389; P = 0.001), AST (>94U/L,OR 8.034, 95%CI 2.200-29.341; P = 0.002), D-dimer (>1.6mg/L, OR 3.167, 95%CI 0.896-11.187; P = 0.042), hemoglobin (<90g/L, OR 14.824, 95%CI 3.713-59.179; P = 0.001), albumin (<25g/L, OR 15.896, 95%CI 3.975-63.566; P = 0.001) were independent predictors of ARDS development in the setting of miliary TB. CONCLUSIONS: Accurate diagnosis, early initiation of anti-tuberculosis therapy and mechanical ventilation are important for the outcome of patients with ARDS caused by miliary TB. DM, ALT, AST, D-dimer, hemoglobin, and albumin are independent predictors of ARDS development in patients with miliary TB.
has issue date	2012-05-20(xsd:dateTime)
bibo:doi	10.1186/1471-2334-12-121
bibo:pmid	22607610
has license	cc-by
sha1sum (hex)	a26b837f1a839bfa722ba5673d875c10fa9a2424
schema:url	https://doi.org/10.1186/1471-2334-12-121
resource representing a document's title	Predictors and outcome of patients with acute respiratory distress syndrome caused by miliary tuberculosis: a retrospective study in Chongqing, China
has PubMed Central identifier	PMC3407496
has PubMed identifier	22607610
schema:publication	BMC Infect Dis
resource representing a document's body	covid:a26b837f1a839bfa722ba5673d875c10fa9a2424#body_text
is schema:about of	named entity 'caused' named entity 'acute respiratory distress syndrome' named entity 'miliary tuberculosis' named entity 'AIM' named entity 'caused' named entity 'Background' named entity 'Miliary tuberculosis' named entity 'clinical characteristics' named entity 'China' named entity 'ARDS' named entity 'case reports' named entity 'oxygen' named entity 'radiographic' named entity '3, 4' named entity 'erythrocyte sedimentation rate' named entity 'ARDS' named entity 'Chronic Health' named entity 'morbidity' named entity 'ARDS' named entity 'anemia' named entity 'fibrin degradation product' named entity 'AST and ALT' named entity 'tuberculosis therapy' named entity 'chronic infection' named entity 'miliary TB' named entity 'histopathological examination' named entity 'risk factor' named entity 'hemoglobin' named entity 'prevalence rate' named entity 'Albumin' named entity 'miliary TB' named entity 'ARDS' named entity 'Mechanical ventilation' named entity 'Positive likelihood ratio' named entity 'pyrazinamide' named entity 'Physiology' named entity 'Chi-squared test' named entity 'miliary TB' named entity 'Hyperglycemia' named entity 'ARDS' named entity 'ARDS' named entity 'acid-fast bacilli' named entity 'case reports' named entity 'AFB' named entity 'true positive' named entity 'hemoglobin' named entity 'hypoproteinemia' named entity 'alveolar cell carcinoma' named entity 'acute respiratory distress syndrome' named entity 'mm Hg' named entity 'hemoglobin' named entity '8.5' named entity 'fibrin' named entity 'human immunodeficiency virus' named entity 'perfusion' named entity 'ARDS' named entity 'ESR' named entity 'miliary TB' named entity 'albumin' named entity 'ESR' named entity 'stratified analysis' named entity 'tissue biopsy' named entity 'nodules' named entity 'morbidity' named entity 'ICU' named entity 'miliary TB' named entity 'tuberculosis therapy' named entity 'miliary TB' named entity 'AST' named entity 'AFB' named entity 'tuberculosis' named entity 'ARDS'

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