About: Score to identify the severity of adult patients with influenza A (H1N1) 2009 virus infection at hospital admission

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About: Score to identify the severity of adult patients with influenza A (H1N1) 2009 virus infection at hospital admission Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Score to identify the severity of adult patients with influenza A (H1N1) 2009 virus infection at hospital admission
Creator	Castilla, J Alonso, J Castro, A Madrid, Spain Domínguez, A Martín, V Godoy, P Soldevila, N Pumarola, T Astray, J Baricot, M Bilbao, A Cantón, R Capelastegui, A Ciber, A Delgado-Rodríguez, Delgado-Rodríguez, M España, P Garin, O Gónzález-Candelas, F Mayoral, J Quintana, J Respiratorias, Enfermedades Tamames, S
source	PMC
abstract	The objective of this paper was to develop a prognostic index for severe complications among hospitalized patients with influenza A (H1N1) 2009 virus infection. We conducted a prospective observational cohort study of 618 inpatients with 2009 H1N1 virus infection admitted to 36 Spanish hospitals between July 2009 and February 2010. Risk factors evaluated included host-related factors and clinical data at admission. We developed a composite index of severe in-hospital complications (SIHC), which included: mortality, mechanical ventilation, septic shock, acute respiratory distress syndrome, and requirement for resuscitation maneuvers. Six factors were independently associated with SIHC: age >45 years, male sex, number of comorbidities, pneumonia, dyspnea, and confusion. From the β parameter obtained in the multivariate model, a weight was assigned to each factor to compute the individual influenza risk score. The score shows an area under the receiver operating characteristic (ROC) curve of 0.77. The SIHC rate was 1.9 % in the low-risk group, 10.3 % in the intermediate-risk group, and 29.6 % in the high-risk group. The odds ratio for complications was 21.8 for the high-risk group compared with the low-risk group. This easy-to-score influenza A (H1N1) 2009 virus infection risk index accurately stratifies patients hospitalized for H1N1 virus infection into low-, intermediate-, and high-risk groups for SIHC.
has issue date	2012-04-24(xsd:dateTime)
bibo:doi	10.1007/s10096-012-1616-8
bibo:pmid	22526871
has license	no-cc
sha1sum (hex)	a256d7e38b822d5706ddb18bc9b93362aab3f82f
schema:url	https://doi.org/10.1007/s10096-012-1616-8
resource representing a document's title	Score to identify the severity of adult patients with influenza A (H1N1) 2009 virus infection at hospital admission
has PubMed Central identifier	PMC7101595
has PubMed identifier	22526871
schema:publication	Eur J Clin Microbiol Infect Dis
resource representing a document's body	covid:a256d7e38b822d5706ddb18bc9b93362aab3f82f#body_text
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