About: Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential
Creator	Xu, Jimin Zhou, Jia Shi, Pei-Yong Li, Hongmin
Source	Medline; PMC
abstract	[Image: see text] The recent outbreak of coronavirus disease 2019 (COVID-19) highlights an urgent need for therapeutics. Through a series of drug repurposing screening campaigns, niclosamide, an FDA-approved anthelminthic drug, was found to be effective against various viral infections with nanomolar to micromolar potency such as SARS-CoV, MERS-CoV, ZIKV, HCV, and human adenovirus, indicating its potential as an antiviral agent. In this brief review, we summarize the broad antiviral activity of niclosamide and highlight its potential clinical use in the treatment of COVID-19.
has issue date	2020-03-03(xsd:dateTime)
bibo:doi	10.1021/acsinfecdis.0c00052
bibo:pmid	32125140
has license	no-cc
sha1sum (hex)	a1ddaf941a4c1a0145ce1af098cf1d9da207ed35
schema:url	https://doi.org/10.1021/acsinfecdis.0c00052
resource representing a document's title	Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential
has PubMed Central identifier	PMC7098069
has PubMed identifier	32125140
schema:publication	ACS Infect Dis
resource representing a document's body	covid:a1ddaf941a4c1a0145ce1af098cf1d9da207ed35#body_text
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