About: The keys to control a coronavirus disease 2019 outbreak in a haemodialysis unit

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The keys to control a coronavirus disease 2019 outbreak in a haemodialysis unit
Creator	Cidraque, Ignacio Fernández-Robres, M López, Marisol López-Herradón, Ana Moreso, Francesc Méndez, Orleans Nin, Jordi Pájaro, Carlota Ramos, Rosa Rincón, Abraham Satorra, Àngels Stuard, Stefano
Source	PMC
abstract	BACKGROUND: The high rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreading represents a challenge to haemodialysis (HD) units. While fast isolation of suspected cases plays an essential role to avoid disease outbreaks, significant rates of asymptomatic cases have recently been described. After detecting an outbreak in one of our HD clinics, wide SARS-CoV-2 screening and segregation of confirmed cases were performed. METHODS: The entire clinic population, 192 patients, underwent testing for SARS-CoV-2 detection by real-time reverse-transcriptase polymerase chain reaction . We used univariate and multivariate logistic regression to define variables involved in SARS-CoV-2 infection in our dialysis unit. Later, we analysed differences between symptomatic and asymptomatic SARS-CoV-2-positive patients. RESULTS: In total, 22 symptomatic and 14 of the 170 asymptomatic patients had a SARS-CoV-2-positive result. Living in a nursing home/homeless [odds ratio (OR) 3.54; P = 0.026], having been admitted to the reference hospital within the previous 2 weeks (OR 5.19; P = 0.002) and sharing health-care transportation with future symptomatic (OR 3.33; P = 0.013) and asymptomatic (OR 4.73; P = 0.002) positive patients were independent risk factors for a positive test. Nine positive patients (25.7%) remained asymptomatic after a 3-week follow-up. We found no significant differences between symptomatic and asymptomatic SARS-CoV-2-positive patients. CONCLUSIONS: Detection of asymptomatic SARS-CoV-2-positive patients is probably one of the key points to controlling an outbreak in an HD unit. Sharing health-care transportation to the dialysis unit, living in a nursing home and having been admitted to the reference hospital within the previous 2 weeks, are major risk factors for SARS-CoV-2 infection.
has issue date	2020-07-13(xsd:dateTime)
bibo:doi	10.1093/ckj/sfaa119
has license	cc-by-nc
schema:url	https://doi.org/10.1093/ckj/sfaa119
resource representing a document's title	The keys to control a coronavirus disease 2019 outbreak in a haemodialysis unit
has PubMed Central identifier	PMC7454433
schema:publication	Clin Kidney J
resource representing a document's body	covid:PMC7454433#body_text
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