About: Comparison of Transmissibility of Coronavirus Between Symptomatic and Asymptomatic Patients: Reanalysis of the Ningbo COVID-19 Data

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Comparison of Transmissibility of Coronavirus Between Symptomatic and Asymptomatic Patients: Reanalysis of the Ningbo COVID-19 Data
Creator	Eysenbach, Gunther Feng, Hui Sanchez, Travis Jin, Huaqing Yin, Guosheng Da Silva, Edson Rashid Soron, Tanjir Zheng, Yao
Source	Medline; PMC
abstract	BACKGROUND: Since the outbreak of the novel coronavirus disease (COVID-19) in December 2019, the coronavirus has spread all over the world at an unprecedented rate. The transmissibility of the coronavirus from asymptomatic patients to healthy individuals has received enormous attention. An important study using COVID-19 data from the city of Ningbo, China, was carried out to estimate and compare the transmission rates of the coronavirus by the symptomatic and asymptomatic patients. However, in the original analysis, the usual chi-square tests were unduly used for some contingency tables with small cell counts including zero, which may violate the assumptions for the chi-square test. OBJECTIVE: We reanalyze the data from the city of Ningbo with more appropriate statistical methods to draw more reliable and sound conclusions on the transmission rates of the coronavirus by the symptomatic and asymptomatic patients. METHODS: We excluded the cases associated with the super-spreader and adopted a more appropriate statistical method, including the permutation test and the Fisher exact test, to reanalyze the COVID-19 data from the city of Ningbo. RESULTS: After excluding the cases related to the super-spreader, the Fisher exact test yields a P value of .84, which indicates stronger evidence of no difference in the transmission rates compared with the original analysis. The odds ratio of the coronavirus transmission rates between the symptomatic and asymptomatic patients is 1.2 with a 95% confidence interval 0.5-2.8. CONCLUSIONS: Through a more in-depth and comprehensive statistical analysis of the Ningbo data, we concluded that there is no difference in the transmission rates of coronavirus between symptomatic and asymptomatic patients.
has issue date	2020-05-28(xsd:dateTime)
bibo:doi	10.2196/19464
bibo:pmid	32442131
has license	cc-by
schema:url	https://doi.org/10.2196/19464
resource representing a document's title	Comparison of Transmissibility of Coronavirus Between Symptomatic and Asymptomatic Patients: Reanalysis of the Ningbo COVID-19 Data
has PubMed Central identifier	PMC7257483
has PubMed identifier	32442131
schema:publication	JMIR Public Health Surveill
resource representing a document's body	covid:PMC7257483#body_text
is schema:about of	named entity 'Ningbo' named entity 'Patients' named entity 'Asymptomatic Patients' named entity 'super-spreader' named entity 'asymptomatic patients' named entity 'public health' named entity 'asymptomatic' named entity 'confidence intervals' named entity 'Wuhan' named entity 'transmissibility' named entity 'Anyang' named entity 'COVID' named entity 'asymptomatic carriers' named entity 'statistically significant' named entity 'asymptomatic' named entity 'chi-square test' named entity 'China' named entity 'COVID' named entity 'asymptomatic' named entity 'asymptomatic' named entity 'asymptomatic' named entity 'King County' named entity 'infection' named entity 'asymptomatic carriers' named entity 'transmissibility' named entity 'sample size' named entity 'significant difference' named entity 'confidence intervals' named entity 'asymptomatic' named entity 'asymptomatic patients' named entity 'coronavirus infection' named entity 'asymptomatic infection' named entity 'permutation test' named entity '95% confidence interval' named entity 'international public health emergency' named entity 'epidemiologic' named entity 'odds ratio' named entity 'Ningbo' named entity 'asymptomatic carriers' named entity 'cruise ship' named entity 'super-spreader' named entity 'asymptomatic' named entity 'confidence intervals' named entity 'permutation test' named entity '95% confidence interval' named entity 'tested positive' named entity 'coronavirus' named entity 'asymptomatic' named entity 'coronavirus' named entity 'coronavirus' named entity 'null hypothesis' named entity 'transmissibility' named entity 'public health' named entity 'hypothesis test' named entity 'coronavirus' named entity 'asymptomatic' named entity 'positive test' named entity 'viral load' named entity 'super-spreader' named entity 'odds ratio' named entity 'Fisher exact test' named entity 'Ningbo' named entity 'COVID-19' named entity 'coronavirus' named entity 'contingency tables' named entity 'travel bans' named entity 'incubation period' named entity 'COVID' named entity 'asymptomatic' named entity 'asymptomatic' named entity 'statistically significant' named entity 'infection' named entity 'asymptomatic patients' named entity 'asymptomatic' named entity 'Fisher exact test'

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