About: Proportion of adult community-acquired pneumonia cases attributable to Streptococcus pneumoniae among Hajj pilgrims in 2016

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About: Proportion of adult community-acquired pneumonia cases attributable to Streptococcus pneumoniae among Hajj pilgrims in 2016 Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Proportion of adult community-acquired pneumonia cases attributable to Streptococcus pneumoniae among Hajj pilgrims in 2016
Creator	Yezli, Saber Alotaibi, Badriah Maashi, Fuad Mushi, Abdulaziz Yassin, Yara Albarrak, Ali Turkistani, Abdulhafiz Alshaer, Mohamed Altaweel, Abdulaziz Elshiekh, Husameddin Grabenstein, John Petigara, Tanaz Seedahmed, Yassein
Source	Elsevier; Medline; PMC
abstract	BACKGROUND: The Hajj mass gathering is a risk for pneumococcal disease. This study was performed to evaluate the proportion of adult community-acquired pneumonia (CAP) cases attributable to Streptococcus pneumoniae among Hajj pilgrims in 2016. To add sensitivity to etiological attribution, a urine antigen test was used in addition to culture-based methods. METHODS: Adult subjects hospitalized with X-ray-confirmed CAP were enrolled prospectively from all general hospitals designated to treat Hajj pilgrims in the holy cities of Mecca and Medina. Patients were treated according to local standard of care and administered the BinaxNow S. pneumoniae urine antigen test. RESULTS: From August 23 to September 23, 2016, a total of 266 patients with CAP were enrolled in the study, 70.6% of whom were admitted to hospitals in Mecca; 53% of the cases were admitted after the peak of Hajj. Patients originated from 43 countries. Their mean age was 65.3 years and the male to female ratio was 2:1. Just over 36% of the cases had diabetes, 10% declared that they were smokers, and 45.4% of cases were treated in the intensive care unit (ICU). The overall case-fatality rate was 10.1%, but was higher among those treated in the ICU and in those with invasive disease. The proportion of CAP cases positive for S. pneumoniae, based on culture or urine antigen test, was 18.0% (95% confidence interval 13.9–23.1%). CONCLUSIONS: CAP during Hajj has an important clinical impact. A proportion of CAP cases among Hajj pilgrims were attributable to S. pneumoniae, a pathogen for which vaccines are available. Additional studies to determine the serotypes causing pneumococcal disease could further inform vaccine policy for Hajj pilgrims.
has issue date	2018-02-21(xsd:dateTime)
bibo:doi	10.1016/j.ijid.2018.02.008
bibo:pmid	29474989
has license	no-cc
sha1sum (hex)	9fa911cd18b7c5a91aa71075b69882176177248c
schema:url	https://doi.org/10.1016/j.ijid.2018.02.008
resource representing a document's title	Proportion of adult community-acquired pneumonia cases attributable to Streptococcus pneumoniae among Hajj pilgrims in 2016
has PubMed Central identifier	PMC7110457
has PubMed identifier	29474989
schema:publication	Int J Infect Dis
resource representing a document's body	covid:9fa911cd18b7c5a91aa71075b69882176177248c#body_text
is schema:about of	named entity 'HEALTH' named entity 'Mecca' named entity 'adult' named entity 'peak' named entity 'study' named entity 'cases' named entity 'Hajj' named entity 'vaccines' named entity 'Medina Region' named entity 'Municipality' named entity 'REGION' named entity 'ADMITTED' named entity 'USED' named entity 'AGE' named entity 'RATIO' named entity 'CASES' named entity 'RISK' named entity 'VACCINES' named entity 'HOSPITALIZED' named entity 'DISEASE' named entity 'CONCLUSIONS' named entity 'MECCA' named entity 'HOSPITALS' named entity 'PROPORTION' named entity 'INFORM' named entity 'POLICY' named entity 'IMPORTANT' named entity 'INVASIVE DISEASE' named entity 'RATE' named entity 'TO ADD' named entity 'CAP' named entity 'CLINICAL' named entity '266' named entity 'ADDITIONAL' named entity 'BASED' named entity 'VACCINE' named entity 'HIGHER' named entity 'THE PEAK' named entity 'ANTIGEN TEST' named entity 'STANDARD OF CARE' named entity 'JUST' named entity 'TREAT' named entity 'STUDIES' named entity 'IS A' named entity 'MALE' named entity 'STUDY' named entity 'POSITIVE FOR' named entity 'STREPTOCOCCUS PNEUMONIAE' named entity 'PATIENTS' named entity 'ADDITION' named entity 'SUBJECTS' named entity 'CITIES' named entity 'OVERALL' named entity 'URINE' named entity 'MEDINA' named entity 'SAUDI ARABIA' named entity 'MUNICIPALITY' named entity 'MEDINA' named entity 'AVAILABLE' named entity 'GENERAL HOSPITALS' named entity 'SENSITIVITY' named entity 'GENERAL' named entity 'INTENSIVE CARE UNIT' named entity 'THEIR' named entity '10%' named entity 'ICU' named entity 'ATTRIBUTABLE' named entity 'DIABETES' named entity 'SEROTYPES'

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