About: Genetic variability human respiratory syncytial virus subgroups A and B in Turkey during six successive epidemic seasons, 2009‐2015

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About: Genetic variability human respiratory syncytial virus subgroups A and B in Turkey during six successive epidemic seasons, 2009‐2015 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Genetic variability human respiratory syncytial virus subgroups A and B in Turkey during six successive epidemic seasons, 2009‐2015
Creator	Bayrakdar, Fatma Korukluoglu, Gulay Ozkul, Aykut Altas, Basak Ayse, \| Can, \| Emine, \| Gokhan Kavuncuoglu, \| Ihsan Durmaz, \| Kocabas, Naci Mısırlıoglu, Dibek Yasemin Cosgun, \|
Source	Medline; PMC
abstract	Human respiratory syncytial virus (HRSV) is most important viral respiratory pathogen of acute lower respiratory tract infections in infants and young children worldwide. The circulating pattern and genetic characteristics in the HRSV attachment glycoprotein gene were investigated in Turkey during six consecutive seasons from 2009 to 2015. HRSVA was dominant in the all epidemic seasons except 2011‐2012 season. Partial sequences of the HVR2 region of the G gene of 479 HRSVA and 135 HRSVB were obtained. Most Turkish strains belonged to NA1, ON1, and BA9, which were the predominant genotypes circulating worldwide. Although three novel genotypes, TR‐A, TR‐BA1, and TR‐BA2, were identified, they were not predominant. Clinical data were available for 69 HRSV‐positive patients who were monitored due to acute lower respiratory tract illness. There were no significant differences in the clinical diagnosis, hospitalization rates, laboratory findings and treatment observed between the HRSVA and HRSVB groups, and co‐infections in this study. The major population afflicted by HRSV infections included infants and children between 13 and 24 months of age. We detected that the CB1, GB5, and THB strains clustered in the same branch with a bootstrap value of 100%. CB‐B and BA12 strains clustered in the same branch with a bootstrap value of 65%. The BA11 genotype was clustered in the BA9 genotype in our study. The present study may contribute on the molecular epidemiology of HRSV in Turkey and provide data for HRSV strains circulating in local communities and other regions worldwide.
has issue date	2017-12-06(xsd:dateTime)
bibo:doi	10.1002/jmv.24983
bibo:pmid	29077212
has license	no-cc
sha1sum (hex)	9ed21829dc619b51fd743cb588b7a89a76d21efd
schema:url	https://doi.org/10.1002/jmv.24983
resource representing a document's title	Genetic variability human respiratory syncytial virus subgroups A and B in Turkey during six successive epidemic seasons, 2009‐2015
has PubMed Central identifier	PMC7166824
has PubMed identifier	29077212
schema:publication	J Med Virol
resource representing a document's body	covid:9ed21829dc619b51fd743cb588b7a89a76d21efd#body_text
is schema:about of	named entity 'epidemic' covid:arg/9ed21829dc619b51fd743cb588b7a89a76d21efd named entity 'gene' named entity 'epidemic' named entity 'human respiratory syncytial virus' named entity 'Genetic variability' named entity 'Turkey' named entity 'bronchiolitis' named entity 'Applied Biosystems' named entity 'nucleotide diversity' named entity 'Sequence data' named entity 'HRSV' named entity 'genotype' named entity 'Turkey' named entity 'amino acids' named entity 'nested PCR' named entity 'gene' named entity 'primers' named entity 'infection' named entity 'RNA genome' named entity 'Gel Extraction' named entity 'HRSV' named entity 'HVR2' named entity 'PCR' named entity 'HRSV' named entity 'HVR1' named entity 'antigenic' named entity 'CB1' named entity 'PCR' named entity 'SPSS' named entity 'ectodomain' named entity 'virus' named entity 'Taq DNA polymerase' named entity 'vaccine' named entity 'amino acid' named entity 'genotype' named entity 'gene' named entity 'NS2' named entity 'genotypes' named entity 'PCR' named entity 'BA9' named entity 'genotype' named entity 'HVR2' named entity 'gRNA' named entity 'genotype' named entity 'genetic analysis' named entity 'epidemics' named entity 'genotype' named entity 'HVR2' named entity 'temperate regions' named entity 'genotypes' named entity 'China' named entity 'GB5' named entity 'evolution' named entity 'viruses' named entity 'GenBank' named entity 'sequence alignments' named entity 'HRSV' named entity 'ClustalW' named entity 'oligosaccharides' named entity 'BA11' named entity 'Chicago' named entity 'HRSV' named entity 'carboxy terminus' named entity 'epidemic' named entity 'genetic analysis' named entity 'bronchiolitis' named entity 'bronchiolitis' named entity 'Canada' named entity 'single-stranded'

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