About: Coast-to-coast spread of SARS-CoV-2 in the United States revealed by genomic epidemiology

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About: Coast-to-coast spread of SARS-CoV-2 in the United States revealed by genomic epidemiology Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Coast-to-coast spread of SARS-CoV-2 in the United States revealed by genomic epidemiology
Creator	Watts, Alexander Hodcroft, Emma Grubaugh, Nathan Landry, Marie Loman, Nicholas Neher, Richard Alpert, Tara Brito, Anderson Cheemarla, Nagarjuna Downing, Randy Ehrlich, Hanna Fauver, Joseph Foxman, Ellen Kalinich, Chaney Ko, Albert Muyombwe, Anthony Neugebauer, Karla Ott, Isabel Petrone, Mary Quick, Joshua Razeq, Jafar Shioda, Kayoko Vogels, Chantal Wyllie, Anne
Source	MedRxiv; Medline; PMC
abstract	Since its emergence and detection in Wuhan, China in late 2019, the novel coronavirus SARS-CoV-2 has spread to nearly every country around the world, resulting in hundreds of thousands of infections to date. The virus was first detected in the Pacific Northwest region of the United States in January, 2020, with subsequent COVID-19 outbreaks detected in all 50 states by early March. To uncover the sources of SARS-CoV-2 introductions and patterns of spread within the U.S., we sequenced nine viral genomes from early reported COVID-19 patients in Connecticut. Our phylogenetic analysis places the majority of these genomes with viruses sequenced from Washington state. By coupling our genomic data with domestic and international travel patterns, we show that early SARS-CoV-2 transmission in Connecticut was likely driven by domestic introductions. Moreover, the risk of domestic importation to Connecticut exceeded that of international importation by mid-March regardless of our estimated impacts of federal travel restrictions. This study provides evidence for widespread, sustained transmission of SARS-CoV-2 within the U.S. and highlights the critical need for local surveillance.
has issue date	2020-03-26(xsd:dateTime)
bibo:doi	10.1101/2020.03.25.20043828
bibo:pmid	32511630
has license	cc-by-nc-nd
sha1sum (hex)	9e90986a075d7593343a2d7c49b71d1fb686cca4
schema:url	https://doi.org/10.1101/2020.03.25.20043828
resource representing a document's title	Coast-to-coast spread of SARS-CoV-2 in the United States revealed by genomic epidemiology
has PubMed Central identifier	PMC7276058
has PubMed identifier	32511630
schema:publication	medRxiv
resource representing a document's body	covid:9e90986a075d7593343a2d7c49b71d1fb686cca4#body_text
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