About: Phage display in the study of infectious diseases

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Phage display in the study of infectious diseases
Creator	Henderson, Brian Mullen, Lisa Nair, Sean Rycroft, Andrew Ward, John
Source	Elsevier; Medline; PMC
abstract	Microbial infections are dependent on the panoply of interactions between pathogen and host and identifying the molecular basis of such interactions is necessary to understand and control infection. Phage display is a simple functional genomic methodology for screening and identifying protein–ligand interactions and is widely used in epitope mapping, antibody engineering and screening for receptor agonists or antagonists. Phage display is also used widely in various forms, including the use of fragment libraries of whole microbial genomes, to identify peptide–ligand and protein–ligand interactions that are of importance in infection. In particular, this technique has proved successful in identifying microbial adhesins that are vital for colonization.
has issue date	2006-03-31(xsd:dateTime)
bibo:doi	10.1016/j.tim.2006.01.006
bibo:pmid	16460941
has license	els-covid
sha1sum (hex)	9d7e0b54e09b1b862b1c95a398c6abe0bef0f089
schema:url	https://doi.org/10.1016/j.tim.2006.01.006
resource representing a document's title	Phage display in the study of infectious diseases
has PubMed Central identifier	PMC7127285
has PubMed identifier	16460941
schema:publication	Trends in Microbiology
resource representing a document's body	covid:9d7e0b54e09b1b862b1c95a398c6abe0bef0f089#body_text
is schema:about of	named entity 'STUDY' named entity 'INFECTIOUS DISEASES' named entity 'PHAGE DISPLAY' named entity 'Phage display' named entity 'phage genome' named entity 'phage display' named entity 'infection' named entity 'capsular polysaccharide' named entity 'ligand' named entity 'protein' named entity 'ligand' named entity 'laminin' named entity 'Polyclonal' named entity 'single-chain' named entity 'protein' named entity 'Neisseria meningitidis' named entity '2, 3' named entity 'phage' named entity 'phage display' named entity 'Anopheles' named entity 'carbohydrate' named entity 'pathogens' named entity 'clones' named entity 'pIII' named entity 'angiogenesis' named entity 'parasite' named entity 'Streptococcus equi' named entity 'receptor agonists' named entity 'biomaterials' named entity 'leucine zipper' named entity 'phage display' named entity 'microbe' named entity 'serum or plasma' named entity 'protein' named entity 'fragment libraries' named entity 'antibiotic resistance' named entity 'gene' named entity 'microbial' named entity 'clones' named entity 'salivary gland' named entity 'genomic DNA' named entity 'malaria' named entity 'Bacillus subtilis' named entity 'vaccine' named entity 'pathogenesis' named entity 'comparative genomics' named entity 'Anopheles' named entity 'genetic techniques' named entity 'C-terminal domains' named entity 'vaccines' named entity 'leucine zipper' named entity 'peptides' named entity 'gene' named entity 'phage display' named entity 'immune responses' named entity 'phage' named entity 'cell surface' named entity 'gene' named entity 'phage' named entity 'filamentous phage' named entity 'clones' named entity 'phage display library' named entity 'adhesins' named entity 'M13' named entity 'cDNA' named entity 'phage display' named entity 'P. aeruginosa' named entity 'DNA fragments' named entity 'peptides' named entity 'infectious process' named entity 'coat proteins' named entity 'recombinant antibodies' named entity 'recombinant' named entity 'phage' named entity 'ECM' named entity 'eluted' named entity 'NPLs'

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