About: Investigation of Compatibility of SARS-CoV-2 RT-PCR Kits Containing Different Gene Targets During COVID-19 Pandemic

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About: Investigation of Compatibility of SARS-CoV-2 RT-PCR Kits Containing Different Gene Targets During COVID-19 Pandemic Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Investigation of Compatibility of SARS-CoV-2 RT-PCR Kits Containing Different Gene Targets During COVID-19 Pandemic
Creator	Sayan, Murat Akhan, Sıla Doluca, Osman Sarıgul, Figen
Source	MedRxiv
abstract	Aim:In the diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), reverse transcriptase-polymerase chain reaction (RT-PCR) technique is often used. We evaluated the compatibility of SARS-CoV-2 RT-PCR kits containing different gene targets during the pandemic. Materials and methods: Samples were tested by Bio-Speddy (RdRp gene) and Diagnovital (RdRp+E genes). The correlation between two assays were determined by Deming regression and chi-square heatmap analyses. Results: Diagnovital PCR kit showed in a constricted range and conveniently exponential amplification curves than Bio-Speedy PCR kit. While the correlation increased when a secondary biomarker was added to the kit. Conclusion: In an unknown sample, using together different PCR kits that target different genes during the pandemic situation may provide a more accurate diagnosis of SARS-CoV-2.
has issue date	2020-06-19(xsd:dateTime)
bibo:doi	10.1101/2020.06.17.20133967
has license	medrxiv
sha1sum (hex)	9d6ad47c098da44421d406b0bdac60fbd6a90ffe
schema:url	https://doi.org/10.1101/2020.06.17.20133967
resource representing a document's title	Investigation of Compatibility of SARS-CoV-2 RT-PCR Kits Containing Different Gene Targets During COVID-19 Pandemic
resource representing a document's body	covid:9d6ad47c098da44421d406b0bdac60fbd6a90ffe#body_text
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