About: A Japanese case of COVID‐19: An autopsy report

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About: A Japanese case of COVID‐19: An autopsy report Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A Japanese case of COVID‐19: An autopsy report
Creator	Horiuchi, Hiroshi Yoshimura, Yukihiro Hayashi, Hiroyuki Mitsui, \| Natsuo Tachikawa, \| Nobuyuki Miyata, \| Ohashi, \| Okudela, Koji Sasaki, \| Tsuchiya, Yuki
Source	Medline; PMC
abstract	A 93‐year‐old woman was admitted with a 10‐day history of cough and prostration. Thoracic computed tomography revealed extensive ground‐glass opacities in both the lungs. The polymerase chain reaction test of sputum for severe acute respiratory syndrome‐coronavirus‐2 (SARS‐CoV‐2) was positive. She was treated with antiviral agents and steroid pulse therapy. However, her oxygen saturation gradually declined, and she died 10 days after hospitalization. The most important autopsy finding was fuzzily segmented diffuse alveolar damage (DAD) that expanded from the subpleural to the medial area. No remarkable changes were observed in organs other than the lungs. Therefore, pneumocytes were suggested as the primary target for SARS‐CoV‐2, which might explain why coronavirus infectious disease‐19 is a serious condition. Thus, early treatment is essential to prevent viral replication from reaching a level that triggers DAD.
has issue date	2020-08-13(xsd:dateTime)
bibo:doi	10.1111/pin.13002
bibo:pmid	32794245
has license	no-cc
sha1sum (hex)	9c5a5903c0f32268cdeb196ecfdb7d9b2373f2bc
schema:url	https://doi.org/10.1111/pin.13002
resource representing a document's title	A Japanese case of COVID‐19: An autopsy report
has PubMed Central identifier	PMC7436745
has PubMed identifier	32794245
schema:publication	Pathol Int
resource representing a document's body	covid:9c5a5903c0f32268cdeb196ecfdb7d9b2373f2bc#body_text
is schema:about of	named entity 'EARLY TREATMENT' named entity 'SUBPLEURAL' named entity 'DAY' named entity 'PNEUMOCYTES' named entity 'REVEALED' named entity 'OTHER THAN' named entity 'HISTORY OF' named entity 'REACHING' named entity 'PROSTRATION' named entity 'MEDIAL AREA' named entity 'EXPANDED ' named entity 'positive' named entity 'severe' named entity 'oxygen saturation' named entity 'polymerase' named entity 'woman' named entity 'ground-glass opacities' named entity 'SARS-CoV-2' named entity 'ground-glass opacities' named entity 'antiviral agents' named entity 'SARS-CoV-2' named entity 'coronavirus' named entity 'Thoracic' named entity 'severe acute respiratory syndrome' named entity 'infectious disease' named entity 'autopsy report' named entity 'distal' named entity '1, 2' named entity 'eosinophilic' named entity 'bronchopneumonia' named entity 'respiratory failure' named entity 'mucosa' named entity 'autopsy' named entity 'neutrophils' named entity 'subpleural' named entity 'subpleural' named entity 'renal failure' named entity 'sulbactam' named entity 'subpleural' named entity 'antiviral agents' named entity 'alveoli' named entity 'ACE2' named entity 'COVID' named entity 'keratinized' named entity 'SARS-CoV' named entity 'COVID' named entity 'hydroxychloroquine' named entity 'exudate' named entity 'Pathology' named entity 'case report' named entity 'infectious disease' named entity 'respiratory tract' named entity 'subpleural' named entity 'heart failure' named entity 'autopsy' named entity 'edematous' named entity 'coronavirus' named entity 'alveolar' named entity 'infectious disease' named entity 'fibroblasts' named entity 'cytoplasm' named entity 'English language' named entity 'epithelial cells' named entity 'trachea' named entity 'autopsy' named entity 'DAD' named entity 'COVID' named entity 'lungs' named entity 'methylprednisolone' named entity 'alveolar' named entity 'lung' named entity 'John Wiley & Sons'

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