About: Non-influenza respiratory viruses in adult patients admitted with influenza-like illness: a 3-year prospective multicenter study

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About: Non-influenza respiratory viruses in adult patients admitted with influenza-like illness: a 3-year prospective multicenter study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Non-influenza respiratory viruses in adult patients admitted with influenza-like illness: a 3-year prospective multicenter study
Creator	Lina, Bruno Carrat, Fabrice Vanhems, Philippe Foulongne, Vincent Loubet, Paul Amour, Sélilah Bénézit, François L'honneur, Anne-Sophie Lagathu, Gisèle Lenzi, Nezha Lesieur, Zineb Pronier, Charlotte The, · Alain, Sophie Duval, · Galtier, · Houhou, Nawal Jouneau, · Launay, · Tattevin, · Vallejo, Christine Yolande Costa, ·
topic	covid:9b51e989723866353008e996e44e6a99c55ec2f5#this
Source	Medline; PMC
abstract	PURPOSE: To describe the burden, and characteristics, of influenza-like illness (ILI) associated with non-influenza respiratory viruses (NIRV). METHODS: We performed a prospective, multicenter, observational study of adults admitted with ILI during three influenza seasons (2012–2015). Patients were screened for picornavirus, respiratory syncytial virus (RSV), coronavirus, human metapneumovirus, adenovirus, bocavirus, parainfluenza virus, and influenza, by PCR on nasopharyngeal samples. We excluded patients coinfected with NIRV and influenza. RESULTS: Among 1421 patients enrolled, influenza virus was detected in 535 (38%), and NIRV in 215 (15%), mostly picornavirus (n = 61), RSV (n = 53), coronavirus 229E (n = 48), and human metapneumovirus (n = 40). In-hospital mortality was 5% (NIRV), 4% (influenza), and 5% (no respiratory virus). As compared to influenza, NIRV were associated with age (median, 73 years vs. 68, P = 0.026), chronic respiratory diseases (53% vs. 45%, P = 0.034), cancer (14% vs. 9%, P = 0.029), and immunosuppressive drugs (21% vs. 14%, P = 0.028), and inversely associated with diabetes (18% vs. 25%, P = 0.038). On multivariable analysis, only chronic respiratory diseases (OR 1.5 [1.1–2.0], P = 0.008), and diabetes (OR 0.5 [0.4–0.8], P = 0.01) were associated with NIRV detection. CONCLUSIONS: NIRV are common in adults admitted with ILI during influenza seasons. Outcomes are similar in patients with NIRV, influenza, or no respiratory virus.
has issue date	2020-02-13(xsd:dateTime)
bibo:doi	10.1007/s15010-019-01388-1
bibo:pmid	32056143
has license	no-cc
sha1sum (hex)	9b51e989723866353008e996e44e6a99c55ec2f5
schema:url	https://doi.org/10.1007/s15010-019-01388-1
resource representing a document's title	Non-influenza respiratory viruses in adult patients admitted with influenza-like illness: a 3-year prospective multicenter study
has PubMed Central identifier	PMC7095392
has PubMed identifier	32056143
schema:publication	Infection
resource representing a document's body	covid:9b51e989723866353008e996e44e6a99c55ec2f5#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/9b51e989723866353008e996e44e6a99c55ec2f5
is schema:about of	named entity 'detected' named entity 'coronavirus' named entity 'observational study' named entity '40%' named entity 'INFLUENZA VIRUS' named entity 'COMPARED' named entity 'CONCLUSIONS' named entity 'AGE' named entity 'ENROLLED' named entity 'PURPOSE' named entity 'CHRONIC' named entity 'ADMITTED' named entity 'BURDEN' named entity 'ILI' named entity 'adenovirus' named entity 'ILI' named entity 'median' named entity 'excluded' named entity 'chronic' named entity 'performed' named entity 'seasons' named entity 'samples' named entity 'picornavirus' named entity 'diabetes' named entity 'respiratory' named entity 'influenza-like illness' named entity '229E' named entity 'ILI' named entity 'coronavirus' named entity 'NIRV' named entity 'influenza virus' named entity 'adenovirus' named entity 'influenza' named entity 'immunosuppressive drugs' named entity 'influenza' named entity 'human metapneumovirus' named entity 'viruses' named entity 'influenza' named entity 'NIRV' named entity 'respiratory syncytial virus' named entity 'coinfected' named entity 'virus' named entity 'parainfluenza virus' named entity 'viruses' named entity 'influenza-like illness' named entity 'coronavirus' named entity 'prospective' named entity 'chronic respiratory diseases' named entity 'COPD' named entity 'rapid tests' named entity 'diabetes mellitus' named entity 'Diabetes' named entity 'Paris' named entity 'influenza' named entity 'experimental studies' named entity 'NIRV' named entity 'NIRV' named entity '1.1'

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