About: Clinical and Epidemiological Characteristics of 1,420 European Patients with mild‐to‐moderate Coronavirus Disease 2019

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Clinical and Epidemiological Characteristics of 1,420 European Patients with mild‐to‐moderate Coronavirus Disease 2019
Creator	Hopkins, Claire Laethem, Yves Manto, Mario Ayad, Tareck Barillari, Maria Blecic, Serge Cabaraux, Pierre Calvo-Henriquez, Christian Cammaroto, Giovanni Chekkoury-Idrissi, Younes Coppee, Frederique De Siati, Daniele Delgado, Irene Distinguin, Lea Fakhry, Nicolas Falanga, Chiara Hans, Stéphane Horoi, Mihaela Hsieh, Julien Journe, Fabrice Khalife, Mohamad Lechien, Jerome Lavigne, Philippe Le Bon, Serge Leich, Pierre Martiny, Delphine Michel, Justin Plzak, Jan Radulesco, Thomas Ris, Laurence Rodriguez, Alexandra Rossi, Camelia Saussez, Sven Souchay, Christel Afia, El Cantarella, Giovanna Circiu, Marta Harmegnies, Bernard Huet, Kathy Jouffe, Lionel Mannelli, Giuditta Mat, Quentin Molteni, Gabriele Tucciarone, Manuel Vergez, Sebastien Cherifi, Soraya Chiesa-Estomba, Cornelis, Jean-Philippe Dequanter, Fourneau, Anne-Francoise Giuditta, Mannelli Koenen, Lukas Lechien, Jay Place, Sammy
source	Medline; PMC; WHO
abstract	BACKGROUND: The clinical presentation of European patients with mild‐to‐moderate Covid‐19 infection is still unknown. OBJECTIVE: To study the clinical presentation of Covid‐19 in Europe. METHODS: Patients with positive diagnosis of Covid‐19 were recruited from 18 European hospitals. Epidemiological and clinical data were obtained through a standardized questionnaire. Bayesian analysis was used for analyzing the relationship between outcomes. RESULTS: 1,420 patients completed the study (962 females, 30.7% of health care workers). The mean age of patients was 39.17±12.09 years. The most common symptoms were headache (70.3%), loss of smell (70.2%), nasal obstruction (67.8%), cough (63.2%), asthenia (63.3%), myalgia (62.5%), rhinorrhea (60.1%), gustatory dysfunction (54.2%) and sore throat (52.9%). Fever was reported by on 45.4%. The mean duration of Covid‐19 symptoms of mild‐to‐moderate cured patients was 11.5±5.7 days. The prevalence of symptoms significantly varied according to age and sex. Young patients more frequently had ear, nose, and throat complaints, whereas elderly individuals often presented fever, fatigue and loss of appetite. Loss of smell, headache, nasal obstruction and fatigue were more prevalent in female patients. The loss of smell was a key symptom of mild‐to‐moderate Covid19 patients and was not associated with nasal obstruction and rhinorrhea. Loss of smell persisted at least 7 days after the disease in 37.5% of cured patients. CONCLUSION: The clinical presentation of mild‐to‐moderate Covid‐19 substantially varies according to the age and the sex characteristics of patients. Olfactory dysfunction seems to be an important underestimated symptom of mild‐to‐moderate Covid‐19 that needs to be recognized as such by the WHO.
has issue date	2020-04-30(xsd:dateTime)
bibo:doi	10.1111/joim.13089
bibo:pmid	32352202
has license	no-cc
sha1sum (hex)	9990ebe3b57b7c0e02d2a71a920abbd05edb1f2e
schema:url	https://doi.org/10.1111/joim.13089
resource representing a document's title	Clinical and Epidemiological Characteristics of 1,420 European Patients with mild‐to‐moderate Coronavirus Disease 2019
has PubMed Central identifier	PMC7267446
has PubMed identifier	32352202
schema:publication	J Intern Med
resource representing a document's body	covid:9990ebe3b57b7c0e02d2a71a920abbd05edb1f2e#body_text
is schema:about of	named entity 'Disease' covid:arg/9990ebe3b57b7c0e02d2a71a920abbd05edb1f2e named entity 'Epidemiological' named entity 'infection' named entity '2019' named entity 'Covid' named entity 'California' named entity 'Covid-19' named entity 'gustatory' named entity 'beta-lactam antibiotic' named entity 'DAG' named entity 'Bayesian analysis' named entity 'SARS-CoV-2' named entity 'infection' named entity 'clinical features' named entity 'Covid' named entity 'clinical presentation' named entity 'loss of appetite' named entity 'diagnostic tests' named entity 'gastroesophageal reflux disease' named entity 'fever' named entity 'dyspnea' named entity 'clinical study' named entity 'cough' named entity 'headache' named entity 'infection' named entity 'analgesics' named entity 'Covid'

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