About: Evaluation of clinically asymptomatic high risk infants with congenital cytomegalovirus infection

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About: Evaluation of clinically asymptomatic high risk infants with congenital cytomegalovirus infection Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Evaluation of clinically asymptomatic high risk infants with congenital cytomegalovirus infection
Creator	Pugni, Lorenza Ronchi, Andrea Cantey, Joseph Sánchez, Pablo Garcia, Fabiana Lee, Lizette Owen, Kris Shoup, Angela Varghese, Shawn Vazquez, Liliana Fabio Mosca, • Zeray, •
Source	PMC
abstract	OBJECTIVE: To determine the frequency of abnormal findings on evaluation of neonates with congenital CMV infection who have a normal physical examination STUDY DESIGN: Retrospective, 2-center study (1996–2017) that reviewed results of complete blood cell count and platelets, serum alanine aminotransferase (ALT) and bilirubin concentrations, eye examination, cranial ultrasonography or other neuroimaging, and brainstem evoked responses performed on neonates with congenital CMV infection and a normal physical examination RESULTS: Of 34 infants with congenital CMV infection and a normal physical examination, 56% (19/34) had ≥1 abnormality: 39%, elevated ALT concentration; 45%, abnormal neuroimaging (five, lenticulostriate vasculopathy; six, intraventricular hemorrhage; four, calcifications); 12%, anemia; 16%, thrombocytopenia; and 3%, chorioretinitis. Seven (21%) infants had sensorineural hearing loss, and 18 infants received antiviral therapy. CONCLUSION: Some infants with congenital CMV infection and a normal physical examination had abnormalities on laboratory or neuroimaging evaluation, which in some cases prompted antiviral treatment.
has issue date	2019-10-01(xsd:dateTime)
bibo:doi	10.1038/s41372-019-0501-z
bibo:pmid	31575999
has license	no-cc
sha1sum (hex)	989b91fe665c985b2d3cf995233779f582cf7218
schema:url	https://doi.org/10.1038/s41372-019-0501-z
resource representing a document's title	Evaluation of clinically asymptomatic high risk infants with congenital cytomegalovirus infection
has PubMed Central identifier	PMC7223780
has PubMed identifier	31575999
schema:publication	J Perinatol
resource representing a document's body	covid:989b91fe665c985b2d3cf995233779f582cf7218#body_text
is schema:about of	named entity 'complete blood cell count' named entity 'ALT' named entity 'infection' named entity 'infants' named entity 'Evaluation' named entity 'BILIRUBIN' named entity 'normal' named entity 'eye examination' named entity 'sensorineural hearing loss' named entity 'abnormality' named entity 'infants' named entity 'elevated' named entity 'Objective' named entity 'physical examination' named entity 'intraventricular hemorrhage' named entity 'platelets' named entity 'MRI' named entity 'CMV infection' named entity 'BSER' named entity 'CMV infection' named entity 'CMV infection' named entity 'CMV' named entity 'thalamic' named entity 'hematocrit' named entity 'hepatitis' named entity 'asymptomatic' named entity 'neuroimaging' named entity 'chorioretinitis' named entity 'ophthalmologic' named entity 'infection' named entity 'audiologic' named entity 'pregnancy' named entity 'platelet count' named entity 'direct bilirubin' named entity 'MRI' named entity 'physical examination' named entity 'hearing testing' named entity 'cranial ultrasound' named entity 'asymptomatic' named entity 'neonates' named entity 'normal hearing' named entity 'congenital' named entity 'prenatal care' named entity 'cranial ultrasound' named entity 'Antiviral therapy' named entity 'periventricular' named entity 'ultrasonography' named entity 'Congenital' named entity 'vasculopathy' named entity 'sensorineural hearing loss' named entity 'selection bias' named entity 'hearing loss' named entity 'antiviral treatment' named entity 'neonates' named entity 'PCR test' named entity 'Argentina' named entity 'gestation' named entity 'thalamic' named entity 'ventriculomegaly' named entity 'urine' named entity 'CMV infection' named entity 'infection' named entity 'bilirubin' named entity 'hearing loss' named entity 'ultrasonography' named entity 'infants' named entity 'calcifications' named entity 'Study design' named entity 'neuroimaging' named entity 'determine'

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