About: Temporal Changes of CT Findings in 90 Patients with COVID-19 Pneumonia: A Longitudinal Study

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Temporal Changes of CT Findings in 90 Patients with COVID-19 Pneumonia: A Longitudinal Study
Creator	Zhou, Min Zhang, Xin Hu, Yue Shi, Heshui Dong, Chengjun Li, Chungao Ren, Qianqian Wang, Yuhui
source	Medline; PMC
abstract	BACKGROUND: CT may play a central role in the diagnosis and management of COVID-19 pneumonia. PURPOSE: To perform a longitudinal study to analyze the serial CT findings over time in patients with COVID-19 pneumonia. MATERIALS AND METHODS: During January 16 to February 17, 2020, 90 patients (male:female, 33:57; mean age, 45 years) with COVID-19 pneumonia were prospectively enrolled and followed up until they were discharged or died, or until the end of the study. A total of 366 CT scans were acquired and reviewed by 2 groups of radiologists for the patterns and distribution of lung abnormalities, total CT scores and number of zones involved. Those features were analyzed for temporal change. RESULTS: CT scores and number of zones involved progressed rapidly, peaked during illness days 6-11 (median: 5 and 5), and followed by persistence of high levels. The predominant pattern of abnormalities after symptom onset was ground-glass opacity (35/78 [45%] to 49/79 [62%] in different periods). The percentage of mixed pattern peaked (30/78 [38%]) on illness days 12-17, and became the second most predominant pattern thereafter. Pure ground-glass opacity was the most prevalent sub-type of ground-glass opacity after symptom onset (20/50 [40%] to 20/28 [71%]). The percentage of ground-glass opacity with irregular linear opacity peaked on illness days 6-11 (14/50 [28%)]) and became the second most prevalent subtype thereafter. The distribution of lesions was predominantly bilateral and subpleural. 66/70 (94%) patients discharged had residual disease on final CT scans (median CT scores and zones involved: 4 and 4), with ground-glass opacity (42/70 [60%]) and pure ground-glass opacity (31/42 [74%]) the most common pattern and subtype. CONCLUSION: The extent of lung abnormalities on CT peaked during illness days 6-11. The temporal changes of the diverse CT manifestations followed a specific pattern, which might indicate the progression and recovery of the illness.
has issue date	2020-03-19(xsd:dateTime)
bibo:doi	10.1148/radiol.2020200843
bibo:pmid	32191587
has license	no-cc
sha1sum (hex)	979f72780a5cd2601474850c31d0f1f492bc4dc0
schema:url	https://doi.org/10.1148/radiol.2020200843
resource representing a document's title	Temporal Changes of CT Findings in 90 Patients with COVID-19 Pneumonia: A Longitudinal Study
has PubMed Central identifier	PMC7233482
has PubMed identifier	32191587
schema:publication	Radiology
resource representing a document's body	covid:979f72780a5cd2601474850c31d0f1f492bc4dc0#body_text
is schema:about of	named entity 'discharge' named entity 'pneumonia' named entity 'COVID' named entity 'Pneumonia' named entity 'ground-glass opacity' named entity 'COVID' named entity 'Vienna' named entity 'ground-glass opacity' named entity 'lung' named entity 'symptom' named entity 'symptom' named entity 'COVID-19' named entity 'bronchoalveolar lavage' named entity 'mediastinal lymphadenopathy' named entity 'Union Hospital' named entity 'CT scans' named entity 'Institutional Review Board' named entity 'Ground-glass opacity' named entity 'ground-glass opacity' named entity 'SARS' named entity 'ground-glass opacity' named entity 'Informed consent' named entity 'CT scans' named entity 'reticular opacity' named entity 'viral pneumonia' named entity 'pneumonia' named entity 'SARS-CoV-2' named entity 'ground-glass opacity' named entity '37 days' named entity 'Austria' named entity 'CT scan' named entity 'ground-glass opacity' named entity 'pleural effusion' named entity 'pneumonia' named entity 'pneumonia' named entity 'Tokyo' named entity 'SARS' named entity 'demographic characteristics' named entity 'GE Medical' named entity 'CT scans' named entity 'symptom' named entity 'SARS' named entity 'E4a' named entity 'CT scans' named entity 'pulmonary vein' named entity 'axil' named entity 'ground-glass opacity' named entity 'lung biopsy' named entity 'CT scans' named entity 'Wuhan' named entity 'Ground-glass opacity' named entity 'rRT-PCR' named entity 'R software' named entity 'public health' named entity 'atelectasis' named entity 'radiology' named entity 'radiologists' named entity 'COVID-19' named entity 'pleural effusion' named entity 'CT scans' named entity 'Fleischner Society' named entity 'COVID-19' named entity 'lung' named entity 'reverse transcriptase' named entity 'CT scans' named entity 'symptom' named entity 'influenza' named entity 'CT scans' named entity 'COVID-19' named entity 'pneumonia' named entity 'CT scans' named entity 'pleura' named entity 'mediastinal emphysema' named entity 'Milwaukee'

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