About: Vanadium: History, chemistry, interactions with α-amino acids and potential therapeutic applications

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Vanadium: History, chemistry, interactions with α-amino acids and potential therapeutic applications
Creator	Ciangherotti, Carlos Hernández, Lino Jiménez, Lissette Lubes, Giuseppe Lubes, Vito Villalobos Coa, Valentina Carpio, Edgar
source	Elsevier; Medline; PMC
abstract	Abstract In the last 30 years, since the discovery that vanadium is a cofactor found in certain enzymes of tunicates and possibly in mammals, different vanadium-based drugs have been developed targeting to treat different pathologies. So far, the in vitro studies of the insulin mimetic, antitumor and antiparasitic activity of certain compounds of vanadium have resulted in a great boom of its inorganic and bioinorganic chemistry. Chemical speciation studies of vanadium with amino acids under controlled conditions or, even in blood plasma, are essential for the understanding of the biotransformation of e.g. vanadium antidiabetic complexes at the physiological level, providing clues of their mechanism of action. The present article carries out a bibliographical research emphaticizing the chemical speciation of the vanadium with different amino acids and reviewing also some other important aspects such as its chemistry and therapeutical applications of several vanadium complexes.
has issue date	2018-10-01(xsd:dateTime)
bibo:doi	10.1016/j.ccr.2018.06.002
bibo:pmid	32226092
has license	els-covid
sha1sum (hex)	92a8c04a0201a6d46875ff3b312dd72c9e12a7d1
schema:url	https://doi.org/10.1016/j.ccr.2018.06.002
resource representing a document's title	Vanadium: History, chemistry, interactions with α-amino acids and potential therapeutic applications
has PubMed Central identifier	PMC7094547
has PubMed identifier	32226092
schema:publication	Coordination Chemistry Reviews
resource representing a document's body	covid:92a8c04a0201a6d46875ff3b312dd72c9e12a7d1#body_text
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