About: Structure–function studies have defined two classes of viral membrane-fusion proteins that have radically different architectures but adopt a similar overall 'hairpin' conformation to induce fusion of the viral and cellular membranes and therefore initiate infection. In both classes, the hairpin conformation is achieved after a conformational change is triggered by interaction with the target cell. This review will focus in particular on the properties of the more recently described class II proteins.   Goto Sponge  NotDistinct  Permalink

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  • Structure–function studies have defined two classes of viral membrane-fusion proteins that have radically different architectures but adopt a similar overall 'hairpin' conformation to induce fusion of the viral and cellular membranes and therefore initiate infection. In both classes, the hairpin conformation is achieved after a conformational change is triggered by interaction with the target cell. This review will focus in particular on the properties of the more recently described class II proteins.
Subject
  • Virology
  • Organelles
  • Immune system
  • Epidemiology
  • Infectious diseases
  • MHC Class II
  • Genes
  • Physical organic chemistry
  • Glycoproteins
  • Abnormal clinical and laboratory findings for RBCs
  • Cell anatomy
  • Membrane biology
  • Stereochemistry
  • Microbiology techniques
  • Engineered proteins
  • Isomerism
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