About: Characteristics of patients with COVID-19 during epidemic ongoing outbreak in Wuhan, China

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About: Characteristics of patients with COVID-19 during epidemic ongoing outbreak in Wuhan, China Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Characteristics of patients with COVID-19 during epidemic ongoing outbreak in Wuhan, China
Creator	Liu, Yu Liu, Y Luo, Xiaomin Cancer, Ye Guo, T Guo, Tangxi Jiang, Z Jiang, Zongping Luo, X Wang, B Wang, Benchao Xia, H Xia, Hongxia Xiong, J Xiong, Jun Yan, X Yan, Xiaojie Yang, W Yang, Weize Ye, L Ye, Lu Zhang, Bicheng Zhou, W
Source	MedRxiv
abstract	Background Since Dec 2019, SARS-CoV-2 has caused about fifty thousand patients and over two thousand deaths in Wuhan, China. We reported characteristics of patients with COVID-19 during epidemic ongoing outbreak in Wuhan. Methods Data of COVID-19 patients with clinical outcome in a designated hospital in Wuhan, were retrospectively collected from electronic medical records. Characteristics were compared between patients who died or recovered, and between patients with different disease severity. Results By Feb 25, 2020, 403 patients were enrolled, 100 died and 303 recovered. Most of non-survivors tended to be males, old aged, or with chronic diseases. Duration from illness onset to admission was 9 (7-12) days. Patients with severe or critical illness had more days from onset to admission compared to those with ordinary illness. Lymphopenia, anemia, hypoproteinemia, and abnormal serum sodium were presented in 52.6%, 54.6%, 69.8%, and 21.8% cases, respectively. Patients who died or with severe/critical illness showed increased white blood cell and neutrophil count, serum total bilirubin, creatinine, hypersensitive troponin I, D-dimer, procalcitonin, and C-reactive protein, and decreased red blood cell, lymphocyte, platelet count, and serum albumin on admission compared to those who recovered or with ordinary illness. Complications of acute organ injury and secondary infection were common in patients with COVID-19, especially in non-survivors. Conclusions Multiple homeostasis disturbances were common in patients with severe or critical illness at admission. Early support should be provided, especially for old men with chronic disease, which is vital to control disease progression and reduce mortality of COVID-19 during epidemic ongoing outbreak.
has issue date	2020-03-23(xsd:dateTime)
bibo:doi	10.1101/2020.03.19.20033175
has license	medrxiv
sha1sum (hex)	91b95074a7523331cbe8d85e1afea2422261875e
schema:url	https://doi.org/10.1101/2020.03.19.20033175
resource representing a document's title	Characteristics of patients with COVID-19 during epidemic ongoing outbreak in Wuhan, China
resource representing a document's body	covid:91b95074a7523331cbe8d85e1afea2422261875e#body_text
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