About: Experimental Infection of Piglets with a Korean Strain of Porcine Epidemic Diarrhoea Virus

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About: Experimental Infection of Piglets with a Korean Strain of Porcine Epidemic Diarrhoea Virus Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Experimental Infection of Piglets with a Korean Strain of Porcine Epidemic Diarrhoea Virus
Creator	Chae, C Kim, O
Source	Elsevier; Medline; PMC
abstract	Abstract Thirty colostrum-deprived piglets aged 1 day were inoculated with a Korean strain of porcine epidemic diarrhoea virus (PEDV). The purpose was to elucidate the pathogenicity and viral distribution in PEDV-infected piglets over a period of 60 h, by morphometric analysis, in-situ hybridization and immunohistochemistry. At 24–60 h post-inoculation (hpi), the villous height/crypt depth (VH/CD) ratio of infected pigs was significantly less than that of control pigs. Positive cells typically exhibited a dark black reaction product (in-situ hybridization) or brown reaction product (immunohistochemistry) in the cytoplasm, without background staining. PEDV nucleic acid and antigen were detected in the duodenum, jejunum and ileum of experimentally infected pigs. The results suggested that the Korean strain was virulent and caused severe villous atrophy in the small intestine.
has issue date	2003-07-31(xsd:dateTime)
bibo:doi	10.1016/s0021-9975(02)00170-6
bibo:pmid	12859908
has license	els-covid
sha1sum (hex)	91760140c1ef6559e6e297d61e122d5a027b8436
schema:url	https://doi.org/10.1016/s0021-9975%2802%2900170-6
resource representing a document's title	Experimental Infection of Piglets with a Korean Strain of Porcine Epidemic Diarrhoea Virus
has PubMed Central identifier	PMC7127761
has PubMed identifier	12859908
schema:publication	Journal of Comparative Pathology
resource representing a document's body	covid:91760140c1ef6559e6e297d61e122d5a027b8436#body_text
is schema:about of	named entity 'VIRAL' named entity 'PORCINE EPIDEMIC DIARRHOEA VIRUS' named entity 'SITU HYBRIDIZATION' named entity 'PURPOSE' named entity 'KOREAN' named entity 'CYTOPLASM' named entity 'PERIOD' named entity 'INFECTED' named entity 'SMALL INTESTINE' named entity 'pigs' named entity 'immunohistochemistry' named entity 'black reaction' named entity 'villous' named entity 'jejunum' named entity 'control' named entity 'Infection' named entity 'STRAIN' named entity 'PORCINE EPIDEMIC DIARRHOEA VIRUS' named entity 'INOCULATION' named entity 'CELLS' named entity 'IN-SITU HYBRIDIZATION' named entity 'EXPERIMENTAL INFECTION' named entity 'KOREAN' named entity 'BROWN' named entity 'BLACK' named entity 'DETECTED' named entity 'STRAIN' named entity 'AGED' named entity 'POST' named entity 'VILLOUS ATROPHY' named entity 'SEVERE' named entity 'CAUSED' named entity 'COLOSTRUM' named entity 'CONTROL' named entity 'POSITIVE' named entity 'THIRTY' named entity 'RATIO' named entity 'ANTIGEN' named entity 'MORPHOMETRIC ANALYSIS' named entity '1 DAY' named entity 'VIRULENT' named entity 'JEJUNUM' named entity 'LESS THAN' named entity 'DEPTH' named entity 'HEIGHT' named entity 'PIGS' named entity 'IMMUNOHISTOCHEMISTRY' named entity 'BACKGROUND' named entity 'PATHOGENICITY' named entity 'DISTRIBUTION' named entity 'REACTION PRODUCT' named entity 'STAINING' named entity 'DARK' named entity 'VILLOUS' named entity 'PEDV' named entity 'RESULTS' named entity 'DUODENUM' named entity 'NUCLEIC ACID' named entity 'ILEUM' covid:arg/91760140c1ef6559e6e297d61e122d5a027b8436 named entity 'morphometric analysis' named entity 'product' named entity 'Positive' named entity 'villi' named entity 'villous' named entity 'cytoplasm' named entity 'tissue sections' named entity 'Arteriviridae' named entity 'Kim and Chae' named entity 'villous' named entity 'monoclonal antibody' named entity 'viral protein' named entity 'cross-bred' named entity 'villous atrophy' named entity 'jejunum' named entity 'RNase' named entity 'ileal' named entity 'monoclonal antibody' named entity 'PEDV' named entity 'nucleic acid'

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