About: Influenza virus and factors that are associated with ICU admission, pulmonary co-infections and ICU mortality

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An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Influenza virus and factors that are associated with ICU admission, pulmonary co-infections and ICU mortality
Creator	Bergmans, D Beumer, M Hoedemaekers, C Koch, R Kolwijck, E Oudelashof, A Van Beuningen, D Van De Veerdonk, F Van Der Hoeven, J
Source	Elsevier; Medline; PMC
abstract	Abstract Purpose While most influenza patients have a self-limited respiratory illness, 5–10% of hospitalized patients develop severe disease requiring ICU admission. The aim of this study was to identify influenza-specific factors associated with ICU admission and mortality. Furthermore, influenza-specific pulmonary bacterial, fungal and viral co-infections were investigated. Methods 199 influenza patients, admitted to two academic hospitals in the Netherlands between 01-10-2015 and 01-04-2016 were investigated of which 45/199 were admitted to the ICU. Results A history of Obstructive/Central Sleep Apnea Syndrome, myocardial infarction, dyspnea, influenza type A, BMI > 30, the development of renal failure and bacterial and fungal co-infections, were observed more frequently in patients who were admitted to the ICU, compared with patients at the normal ward. Co-infections were evident in 55.6% of ICU-admitted patients, compared with 20.1% of patients at the normal ward, mainly caused by Staphylococcus aureus, Streptococcus pneumoniae, and Aspergillus fumigatus. Non-survivors suffered from diabetes mellitus and (pre-existent) renal failure more often. Conclusions The current study indicates that a history of OSAS/CSAS, myocardial infarction and BMI > 30 might be related to ICU admission in influenza patients. Second, ICU patients develop more pulmonary co-infections. Last, (pre-existent) renal failure and diabetes mellitus are more often observed in non-survivors.
has issue date	2019-04-30(xsd:dateTime)
bibo:doi	10.1016/j.jcrc.2018.11.013
bibo:pmid	30481669
has license	els-covid
sha1sum (hex)	914d30aff7d43a8398e3239907a40efac57c0632
schema:url	https://doi.org/10.1016/j.jcrc.2018.11.013
resource representing a document's title	Influenza virus and factors that are associated with ICU admission, pulmonary co-infections and ICU mortality
has PubMed Central identifier	PMC7125534
has PubMed identifier	30481669
schema:publication	Journal of Critical Care
resource representing a document's body	covid:914d30aff7d43a8398e3239907a40efac57c0632#body_text
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