About: Successful resolution of dermatophyte mycetoma following terbinafine treatment in two cats

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About: Successful resolution of dermatophyte mycetoma following terbinafine treatment in two cats Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Successful resolution of dermatophyte mycetoma following terbinafine treatment in two cats
Creator	German, A Holden, S Hopkinson, C Mcewan, N Nuttall, T
Source	Medline; PMC
abstract	Microsporum canis sensitive to itraconazole and terbinafine was isolated from two cats presented with generalized dermatophytosis and dermatophyte mycetoma. Itraconazole therapy was withdrawn through lack of efficacy in one cat (a Persian) and unacceptable adverse effects in the other (a Maine Coon). Both cats achieved clinical and mycological cure after 12–14 weeks therapy with 26–31 mg kg(−1) terbinafine every 24 h per os (PO). Clinical signs in the Maine Coon resolved completely after 7 weeks treatment. Four weeks of therapy with additional weekly washes with a 2% chlorhexidine/2% miconazole shampoo following clipping produced a 98% reduction in the Persian cat's mycetoma, which was then surgically excised. Recurrent generalized dermatophytosis in the Persian cat has been managed with pulse therapy with 26 mg kg(−1) terbinafine every 24 h PO for 1 week in every month. No underlying conditions predisposing to dermatophytosis were found in either cat despite extensive investigation. Terbinafine administration was associated with mild to moderate lethargy in the Persian cat, but no other adverse effects or changes in blood parameters were seen. To the best of the authors’ knowledge this is the first report of a dermatophyte mycetoma in a Maine Coon and of successful resolution of this condition in cats following terbinafine therapy.
has issue date	2008-12-01(xsd:dateTime)
bibo:doi	10.1111/j.1365-3164.2008.00712.x
bibo:pmid	19055614
has license	no-cc
sha1sum (hex)	9084e3535b8e57abd773a1c78a797b0b5acc60cf
schema:url	https://doi.org/10.1111/j.1365-3164.2008.00712.x
resource representing a document's title	Successful resolution of dermatophyte mycetoma following terbinafine treatment in two cats
has PubMed Central identifier	PMC7169289
has PubMed identifier	19055614
schema:publication	Vet Dermatol
resource representing a document's body	covid:9084e3535b8e57abd773a1c78a797b0b5acc60cf#body_text
is schema:about of	named entity 'isolated' named entity 'successful' named entity 'cure' named entity 'moderate' named entity 'resolved' named entity 'sensitive' named entity 'Persian cat' named entity 'terbinafine' named entity 'dermatophyte' named entity 'extensive' named entity 'lethargy' named entity 'washes' named entity 'mild' named entity 'adverse effects' named entity 'Microsporum canis' named entity 'cats' named entity 'cats' named entity 'Persian cat' named entity 'Clinical signs' named entity 'adverse effects' named entity 'dermatophytosis' named entity 'shampoo' named entity 'dermatophyte' named entity 'dermatophytosis' named entity 'mycetoma' named entity 'adverse effects' named entity 'dermatophyte' named entity 'fungi' named entity 'alopecia' named entity 'clinical outcome' named entity 'Terbinafine' named entity '12 weeks' named entity 'Dermatophytosis' named entity 'sinus' named entity 'nodules' named entity 'basophilic' named entity 'infection' named entity 'dermatophyte' named entity 'body fat' named entity 'Health Protection Agency' named entity 'haematology' named entity 'dermatophyte' named entity 'biopsy' named entity 'neutered' named entity 'itraconazole' named entity 'granulomatous inflammation' named entity 'ketoconazole' named entity 'periodic acid Schiff' named entity 'Sporanox' named entity 'Maine Coon' named entity 'mycetoma' named entity 'mycetoma' named entity 'los gatos' named entity 'histopathology' named entity 'Persian cats' named entity 'Wood's lamp' named entity 'Neutered' named entity 'infection' named entity 'Dermatophyte' named entity 'multinucleate' named entity 'ergosterol' named entity 'MICs' named entity 'itraconazole' named entity 'terbinafine' named entity 'M. gypseum' named entity 'body weight' named entity 'ad libitum' named entity 'detection bias' named entity 'biopsy' named entity 'Maine Coon' named entity 'fungal culture' named entity 'dermatophyte' named entity 'seborrhoea' named entity 'Dermatophytosis' named entity 'dermatophyte test medium' named entity 'squalene epoxidase' named entity 'Zoonotic'

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