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  • The usefulness of rapid pathogen genotyping is widely recognized, but its effective interpretation and application requires integration into clinical and public health decision-making. How can pathogen genotyping data best be translated to inform disease management and surveillance? Pathogen profiling integrates microbial genomics data into communicable disease control by consolidating phenotypic identity-based methods with DNA microarrays, proteomics, metabolomics and sequence-based typing. Sharing data on pathogen profiles should facilitate our understanding of transmission patterns and the dynamics of epidemics. SUPPLEMENTARY INFORMATION: The online version of this article (doi:10.1038/nrmicro1656) contains supplementary material, which is available to authorized users.
Subject
  • Genetics
  • Infectious diseases
  • Decision-making
  • Polymorphism (biology)
  • Scientific organizations established in 1945
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