About: Transmission dynamics of SARS‐CoV‐2 within families with children in Greece: a study of 23 clusters

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Transmission dynamics of SARS‐CoV‐2 within families with children in Greece: a study of 23 clusters Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Transmission dynamics of SARS‐CoV‐2 within families with children in Greece: a study of 23 clusters
Creator	Kossyvakis, Athanasios Papa, Anna Maltezou, Helena Spanakis, Nikolaos Maltezou, Helen Mentis, Andreas Tsakris, Athanasios Roilides, Emmanuel Exindari, Maria Gioula, Georgia Metallidis, Symeon Papadima, Kalliopi Raftopoulos, Vasilios Froukala, Elisavet Lourida, Athanasia Martinez-Gonzalez, Beatriz Mitsianis, Athanasios Vorou, Rengina
Source	Medline; PMC
abstract	BACKGROUND: There is limited information on SARS‐CoV‐2 infection clustering within families with children. We aimed to study the transmission dynamics of SARS‐CoV‐2 within families with children in Greece. METHODS: We studied 23 family clusters of COVID‐19. Infection was diagnosed by RT‐PCR in respiratory specimens. The level of viral load was categorized as high, moderate, or low based on the cycle threshold values. RESULTS: There were 109 household members (66 adults and 43 children). The median attack rate per cluster was 60% (range: 33.4%‐100%). An adult member with COVID‐19 was the first case in 21 (91.3%) clusters. Transmission of infection occurred from an adult to a child in 19 clusters and/or from an adult to another adult in 12 clusters. There was no evidence of child‐to‐adult or child‐to‐child transmission. In total 68 household members (62.4%) tested positive. Children were more likely to have an asymptomatic SARS‐CoV‐2 infection compared to adults (40% versus 10.5%, p‐value=0.021). In contrast, adults were more likely to develop a severe clinical course compared to children (8.8% versus 0%, p‐value=0.021). In addition, infected children were significantly more likely to have a low viral load while adults were more likely to have a moderate viral load (40.7% and 18.5% versus 13.8% and 51.7%, respectively; p‐value=0.016). CONCLUSIONS: While children become infected by SARS‐CoV‐2, they do not appear to transmit infection to others. Furthermore, children more frequently have an asymptomatic or mild course compared to adults. Further studies are needed to elucidate the role of viral load on these findings. This article is protected by copyright. All rights reserved.
has issue date	2020-08-07(xsd:dateTime)
bibo:doi	10.1002/jmv.26394
bibo:pmid	32767703
has license	no-cc
sha1sum (hex)	8fe723115d03445f06c89faf4581480857aa6c1c
schema:url	https://doi.org/10.1002/jmv.26394
resource representing a document's title	Transmission dynamics of SARS‐CoV‐2 within families with children in Greece: a study of 23 clusters
has PubMed Central identifier	PMC7441283
has PubMed identifier	32767703
schema:publication	J Med Virol
resource representing a document's body	covid:8fe723115d03445f06c89faf4581480857aa6c1c#body_text
is schema:about of	named entity 'limited' named entity 'Transmission' named entity 'transmission' named entity 'infection' named entity 'COVID-19 cases' named entity 'SARS-CoV-2' named entity 'viral load' named entity 'immune response' named entity 'asymptomatic' named entity 'sample size' named entity 'SPSS' named entity 'SARS-CoV-2' named entity 'ICU' named entity 'lung' named entity 'Index case' named entity 'infection' named entity 'Thessaloniki' named entity 'Athens' named entity 'infection' named entity 'COVID-19' named entity 'COVID' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2' named entity 'China' named entity 'Greece' named entity 'COVID' named entity 'Switzerland' named entity 'COVID' named entity 'viral load' named entity 'Wuhan' named entity 'COVID-19 cases' named entity 'Greece' named entity 'coronavirus 2' named entity 'infection' named entity 'COVID-19 cases' named entity 'descriptive form' named entity 'asymptomatic infection' named entity 'infection' named entity 'COVID-19 cases' named entity 'intensive care unit' named entity 'infection' named entity 'SARS-CoV-2' named entity 'index case' named entity 'asymptomatic infection' named entity 'viral load' named entity 'community-acquired' named entity 'Greece' named entity 'statistically significant' named entity 'lockdown' named entity 'polymerase chain reaction' named entity 'February 26' named entity 'National Public Health Organization' named entity 'SARS-CoV-2' named entity 'China' named entity 'virus' named entity 'p-value' named entity 'SARS-CoV-2' named entity 'Contact tracing' named entity 'PCR' named entity 'SARS-CoV-2' named entity 'COVID' named entity 'China' named entity 'epidemiological' named entity 'infection'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software