About: Tissue distribution of a feline AGP related protein (fAGPrP) in cats with feline infectious peritonitis (FIP)

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About: Tissue distribution of a feline AGP related protein (fAGPrP) in cats with feline infectious peritonitis (FIP) Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : covidontheweb.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Tissue distribution of a feline AGP related protein (fAGPrP) in cats with feline infectious peritonitis (FIP)
Creator	Ceciliani, F Giordano, A Paltrinieri, S Sironi, G
Source	Elsevier; Medline; PMC
abstract	Abstract Feline α 1-acid glycoprotein (fAGP) increases during feline infectious peritonitis (FIP). We have recently identified a 29 kDa protein that we named feline AGP-related protein (fAGPrP) due to its cross-reactivity with an anti-human AGP monoclonal antibody. In this work we describe the tissue distribution of fAGPrP during FIP, and its relationship with feline coronavirus (FCoV) and myeloid cells. Tissues from five control cats and from 15 cats with FIP were examined by immunohistochemistry using monoclonal antibodies against human AGP, FCoV and myeloid antigens. Diffuse fAGPrP positivity within the lesions, likely due to vascular plasma leakage, endothelial and epithelial lining were detectable. Compared to controls, fAGPrP-expressing cells often increased in number and were diffusely distributed in lymph nodes, as usually occurs for IgM-producing plasma cells during early immune responses. These findings did not depend on the presence of FCoVs or of myeloid cells, suggesting that fAGPrP is not directly involved in the pathogenesis of FIP.
has issue date	2004-04-30(xsd:dateTime)
bibo:doi	10.1016/j.jfms.2003.08.012
bibo:pmid	15123154
has license	els-covid
sha1sum (hex)	8f61eb2da6f8e947a03bdf5afa69c49d9e892fb8
schema:url	https://doi.org/10.1016/j.jfms.2003.08.012
resource representing a document's title	Tissue distribution of a feline AGP related protein (fAGPrP) in cats with feline infectious peritonitis (FIP)
has PubMed Central identifier	PMC7129350
has PubMed identifier	15123154
schema:publication	Journal of Feline Medicine & Surgery
resource representing a document's body	covid:8f61eb2da6f8e947a03bdf5afa69c49d9e892fb8#body_text
is schema:about of	named entity 'describe' named entity 'lymph nodes' named entity 'acid' named entity 'cross-reactivity' named entity 'PROTEIN ' named entity 'FELINE INFECTIOUS PERITONITIS' named entity 'AGP' named entity 'LIKELY' named entity 'COMPARED' named entity 'MONOCLONAL ANTIBODIES' named entity 'LYMPH NODES' named entity 'CROSS' named entity 'EXAMINED' named entity 'DISTRIBUTED' named entity 'HAVE' named entity 'USUALLY' named entity 'LESIONS' named entity 'IGM' named entity 'DIRECTLY' named entity 'DEPEND' named entity 'NAMED' named entity 'FINDINGS' named entity 'FIP' named entity 'ANTIGENS' named entity 'TISSUE DISTRIBUTION' named entity 'GLYCOPROTEIN' covid:arg/8f61eb2da6f8e947a03bdf5afa69c49d9e892fb8 named entity 'FELINE' named entity 'INCREASED' named entity 'LINING' named entity 'ACID' named entity 'INVOLVED' named entity 'IMMUNE RESPONSES' named entity 'RELATIONSHIP' named entity 'FELINE INFECTIOUS PERITONITIS' named entity 'CATS' named entity 'TISSUE DISTRIBUTION' named entity 'RELATED' named entity 'PROTEIN ' named entity 'EPITHELIAL' named entity 'DETECTABLE' named entity 'DUE TO' named entity 'CONTROL' named entity 'DID' named entity 'MYELOID CELLS' named entity 'HUMAN' named entity 'RECENTLY' named entity 'USING' named entity 'IMMUNOHISTOCHEMISTRY' named entity 'THESE' named entity 'DESCRIBE' named entity 'PATHOGENESIS' named entity 'PRESENCE OF' named entity 'PRODUCING' named entity 'MONOCLONAL ANTIBODY' named entity 'IDENTIFIED' named entity '29 KDA PROTEIN' named entity 'CATS' named entity 'VASCULAR' named entity 'WORK' named entity 'NUMBER' named entity 'AGP' named entity 'MYELOID' named entity 'PLASMA CELLS' named entity 'LEAKAGE' named entity 'TISSUES' named entity 'RELATED' named entity 'FELINE CORONAVIRUS' named entity 'ENDOTHELIAL' named entity 'INCREASES' named entity 'FELINE' named entity 'ITS' named entity 'EARLY' named entity 'CELLS' named entity 'REACTIVITY' named entity 'DIFFUSE' named entity 'PLASMA' named entity 'monoclonal antibodies'

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